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LT - (R)-1(2,2-difluorbenzo(d)(1,3)dioksol-5-il)-N-(1-(2,3-dihidroksipropil)-6-fluor-2-(1-hidroksi-2-metilpropan-2-il)-1H-indol-5-il)-ciklopropankarboksamido kieta amorfinės formos dispersija
EN - SOLID DISPERSION OF AMORPHOUS FORM OF (R)-1(2,2-DIFLUOROBENZO(D)(1,3)DIOXOL-5-YL)-N-(1-(2,3-DIHYDROXYPROPYL)-6-FLUORO-2-(1-HYDROXY-2-METHYLPROPAN-2-YL)-1H-INDOL-5-YL)-CYCLOPROPANECARBOXAMIDE

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Patent in force

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. A61K 9/10 (2006.01)
C07D 405/12 (2006.01)
A61P 11/00 (2006.01)
A61K 31/404 (2006.01)
European patent
(11) Number of the document 2826776
(13) Kind of document T
(96) European patent application number 14172991.3
Date of filing the European patent application 2011-03-25
(97) Date of publication of the European application 2015-01-21
(45) Date of publication and mention of the grant of the patent 2020-11-25
(46) Date of publication of the claims translation 2021-01-11
Priority applications
(30) Number Date Country code
317376 P 2010-03-25 US
319953 P 2010-04-01 US
321636 P 2010-04-07 US
321561 P 2010-04-07 US
Inventors
(72)
Keshavarz-Shokri, Ali, US
Zhang, Beili, US
Alcacio, Tim Edward, US
Lee, Elaine Chungmin, US
Zhang, Yuegang, US
Krawiec, Mariusz, US
Grantee
(73) Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA 02210, US
Attorney or representative
(74) Jurga PETNIŪNAITĖ, AAA Law, A. Goštauto g. 40B, Verslo centras "Dvyniai", LT-03163 Vilnius, LT
Title
(54) (R)-1(2,2-difluorbenzo(d)(1,3)dioksol-5-il)-N-(1-(2,3-dihidroksipropil)-6-fluor-2-(1-hidroksi-2-metilpropan-2-il)-1H-indol-5-il)-ciklopropankarboksamido kieta amorfinės formos dispersija
  SOLID DISPERSION OF AMORPHOUS FORM OF (R)-1(2,2-DIFLUOROBENZO(D)(1,3)DIOXOL-5-YL)-N-(1-(2,3-DIHYDROXYPROPYL)-6-FLUORO-2-(1-HYDROXY-2-METHYLPROPAN-2-YL)-1H-INDOL-5-YL)-CYCLOPROPANECARBOXAMIDE
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2027-03-25