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LT - (1S)-4,5-dimethoksi-1-(metilaminometil)-benzociklobutano, jo rūgšties adityvinių druskų gavimo būdas ir jo panaudojimas ivabradino ir jo farmaciškai priimtinos rūgšties adityvinių druskų sintezei
EN - Process for the preparation of (1S)-4,5-dimethoxy-1-(methylaminomethyl)-benzocyclobutane, acid addition salts thereof and its use for the synthesis of ivabradine and for its pharmaceutically acceptable acid addition salts

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Patent expired

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07C 213/10 (2006.01)
C07C 217/56 (2006.01)
C07B 57/00 (2006.01)
European patent
(11) Number of the document 1598333
(13) Kind of document T
(96) European patent application number 05290384.6
Date of filing the European patent application 2005-02-21
(97) Date of publication of the European application 2005-11-23
(45) Date of publication and mention of the grant of the patent 2006-10-18
(46) Date of publication of the claims translation 2007-02-26
Priority applications
(30) Number Date Country code
0405453 2004-05-19 FR
Inventors
(72)
Lerestif, Jean-Michel, FR
Gonzalez-Blanco, Isaac, ES
Lecouve, Jean-Pierre, FR
Brigot, Daniel, FR
Grantee
(73) Les Laboratoires Servier, 12, Place de La Défense, 92415 Courbevoie Cedex, FR
Attorney or representative
(74) Reda ŽABOLIENĖ, METIDA, Verslo centras "VERTAS", Gynėjų g. 16, LT-01109 Vilnius, LT
Title
(54) (1S)-4,5-dimethoksi-1-(metilaminometil)-benzociklobutano, jo rūgšties adityvinių druskų gavimo būdas ir jo panaudojimas ivabradino ir jo farmaciškai priimtinos rūgšties adityvinių druskų sintezei
  Process for the preparation of (1S)-4,5-dimethoxy-1-(methylaminomethyl)-benzocyclobutane, acid addition salts thereof and its use for the synthesis of ivabradine and for its pharmaceutically acceptable acid addition salts
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Payment date Validity (years) Amount
2024-01-26 347.00 EUR