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LT - Pharmaceutical formulations comprising salts of (5S,8S)-8-[{(1 R)-1-(3,5-Bis-trifluoromethyl)phenyl]- ethoxy}-methyl]-8-phenyl-1 ,7-diazaspiro[4.5]decan-2-one and their medical use
EN - Pharmaceutical formulations comprising salts of (5S,8S)-8-[{(1 R)-1-(3,5-Bis-trifluoromethyl)phenyl]- ethoxy}-methyl]-8-phenyl-1 ,7-diazaspiro[4.5]decan-2-one and their medical use

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Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. A61K 9/16
A61K 9/48
A61K 31/438
A61P 1/08
European patent
(11) Number of the document 2004148
(13) Kind of document T
(96) European patent application number 07774641.0
Date of filing the European patent application 2007-04-04
(97) Date of publication of the European application 2008-12-24
(45) Date of publication and mention of the grant of the patent 2015-07-15
(46) Date of publication of the claims translation
PCT application
(86) Number PCT/US2007/008345
Date 2007-04-04
PCT application publication
(87) Number WO 2007/114921
Date 2007-10-11
Priority applications
(30) Number Date Country code
789514 P 2006-04-05 US
Inventors
(72)
QIU, Zhihui, US
REYDERMAN, Larisa, US
Grantee
(73) OPKO Health, Inc., 4400 Biscayne Blvd., Miami, FL 33137, US
Title
(54) Pharmaceutical formulations comprising salts of (5S,8S)-8-[{(1 R)-1-(3,5-Bis-trifluoromethyl)phenyl]- ethoxy}-methyl]-8-phenyl-1 ,7-diazaspiro[4.5]decan-2-one and their medical use
  Pharmaceutical formulations comprising salts of (5S,8S)-8-[{(1 R)-1-(3,5-Bis-trifluoromethyl)phenyl]- ethoxy}-methyl]-8-phenyl-1 ,7-diazaspiro[4.5]decan-2-one and their medical use