Patent details

EN | LT

LT - PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 8-[{1-(3,5-BIS-(TRIFLUOROMETHYL)PHENYL)-ETHOXY}-METHYL]-8-PHENYL-1,7-DIAZA-SPIRO[4.5]DECAN-2-ONE COMPOUNDS

EN - PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 8-[{1-(3,5-BIS-(TRIFLUOROMETHYL)PHENYL)-ETHOXY}-METHYL]-8-PHENYL-1,7-DIAZA-SPIRO[4.5]DECAN-2-ONE COMPOUNDS

Legal status

Patent not validated

Bibliographic data

Indications of the International Patent Classification (IPC)
(51)	INT.CL.	C07D 211/38
		C07D 471/10
		C07D 498/10

European patent
(11)	Number of the document	2137151
(13)	Kind of document	T
(96)	European patent application number	08742144.2
	Date of filing the European patent application	2008-03-20
(97)	Date of publication of the European application	2009-12-30
(45)	Date of publication and mention of the grant of the patent	2016-05-11
(46)	Date of publication of the claims translation

PCT application
(86)	Number	PCT/US2008/003640
	Date	2008-03-20

PCT application publication
(87)	Number	WO 2008/118328
	Date	2008-10-02

Priority applications
(30)	Number	Date	Country code
	919666 P	2007-03-22	US

Inventors
(72)	MERGELSBERG, Ingrid, US SCHERER, Dominik, Hermann, CH HUTTENLOCH, Monika, Erika, CH TSUI, Hon-chung, US PALIWAL, Sunil, US SHIH, Neng-Yang, US

Grantee
(73)	OPKO Health, Inc., 4400 Biscayne Blvd., Miami, FL 33137, US

Title
(54)	PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 8-[{1-(3,5-BIS-(TRIFLUOROMETHYL)PHENYL)-ETHOXY}-METHYL]-8-PHENYL-1,7-DIAZA-SPIRO[4.5]DECAN-2-ONE COMPOUNDS
	PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 8-[{1-(3,5-BIS-(TRIFLUOROMETHYL)PHENYL)-ETHOXY}-METHYL]-8-PHENYL-1,7-DIAZA-SPIRO[4.5]DECAN-2-ONE COMPOUNDS