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LT - Tarpiniai junginiai, skirti 8-[{1-(3,5-bis-(trifluormetil)fenil)-etoksi}-metil]-8-fenil-1,7-diaza-spiro[4.5]dekan-2-ono sintezei
EN - INTERMEDIATES FOR THE SYNTHESIS OF 8-[{1-(3,5-BIS-(TRIFLUOROMETHYL)PHENYL)-ETHOXY}-METHYL]-8-PHENYL-1,7-DIAZA-SPIRO[4.5]DECAN-2-ONE COMPOUNDS

Legal status

Patent lapsed (non-payment of fees)

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07D 207/26 (2006.01)
C07D 471/10 (2006.01)
C07D 498/04 (2006.01)
European patent
(11) Number of the document 2346823
(13) Kind of document T
(96) European patent application number 09792268.6
Date of filing the European patent application 2009-09-04
(97) Date of publication of the European application 2011-07-27
(45) Date of publication and mention of the grant of the patent 2015-08-19
(46) Date of publication of the claims translation 2015-11-25
PCT application
(86) Number PCT/US2009/056020
Date 2009-09-04
PCT application publication
(87) Number WO 2010/028232
Date 2010-03-11
Priority applications
(30) Number Date Country code
94474 P 2008-09-05 US
Inventors
(72)
WU, George, G., US
WERNE, Gerald, DE
FU, Xiaoyong, US
ORR, Robert, K., US
CHEN, Frank, Xing, US
CUI, Jian, US
SPRAGUE, Victoria, M., US
ZHANG, Fucheng, US
XIE, Ji, US
ZENG, Liansheng, US
CASTELLANOS, Louis, Peter, US
CHEN, Yuyin, US
POIRIER, Marc, US
MERGELSBERG, Ingrid, US
Grantee
(73) OPKO Health, Inc., 4400 Biscayne Blvd. Suite 1180, Miami, FL 33137, US
Attorney or representative
(74) Genė Ona SRUOGIENĖ, UAB TARPINĖ, A.P.Kavoliuko g. 24-152, LT-04328 Vilnius, LT
Title
(54) Tarpiniai junginiai, skirti 8-[{1-(3,5-bis-(trifluormetil)fenil)-etoksi}-metil]-8-fenil-1,7-diaza-spiro[4.5]dekan-2-ono sintezei
  INTERMEDIATES FOR THE SYNTHESIS OF 8-[{1-(3,5-BIS-(TRIFLUOROMETHYL)PHENYL)-ETHOXY}-METHYL]-8-PHENYL-1,7-DIAZA-SPIRO[4.5]DECAN-2-ONE COMPOUNDS
Last renewal fee
Payment date Validity (years) Amount
2019-08-20 11 289.00 EUR
Legal status
Patent lapsed (non-payment of fees)
Invalidation date 2020-09-04