LT - A composition comprising (-)-trans-3-(5,6-dihydro-4h-pyrrolo [3,2,1-ij] quinolin-1-yl)-4-(1h-indol-3-yl) pyrrolidine-2, 5-dione in combination with sorafenib, sunitinib or erlotinib
EN - A composition comprising (-)-trans-3-(5,6-dihydro-4h-pyrrolo [3,2,1-ij] quinolin-1-yl)-4-(1h-indol-3-yl) pyrrolidine-2, 5-dione in combination with sorafenib, sunitinib or erlotinib
Legal status
Patent not validated
Bibliographic data
Indications of the International Patent Classification (IPC)
(51) |
INT.CL. |
A61K 31/517 |
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A61K 31/4745 |
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A61K 31/4412 |
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A61K 31/404 |
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A61K 45/06 |
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A61P 35/00 |
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European patent
(11) |
Number of the document |
2396003 |
(13) |
Kind of document |
T |
(96) |
European patent application number |
10704696.3 |
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Date of filing the European patent application |
2010-02-11 |
(97) |
Date of publication of the European application |
2011-12-21 |
(45) |
Date of publication and mention of the grant of the patent |
2013-04-17
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(46) |
Date of publication of the claims translation |
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PCT application
(86) |
Number |
PCT/US2010/023893 |
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Date |
2010-02-11 |
PCT application publication
(87) |
Number |
WO 2010/093789 |
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Date |
2010-08-19 |
Priority applications
(30) |
Number |
Date |
Country code |
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152138 P |
2009-02-12
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US |
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170471 P |
2009-04-17
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US |
Inventors
(72) |
CHAN, Thomas C.K., US
FRANCE, Dennis S., US
ISHII, Kenichi, JP
PUCCI, Paolo, US
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Grantee
(73) |
Kyowa Hakko Kirin Co., Ltd.,
1-6-1, Ohtemachi, Chiyoda-ku, Tokyo 100-8185,
JP
ArQule, Inc.,
19 Presidential Way, Woburn, MA 01801,
US
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Title
(54) |
A composition comprising (-)-trans-3-(5,6-dihydro-4h-pyrrolo [3,2,1-ij] quinolin-1-yl)-4-(1h-indol-3-yl) pyrrolidine-2, 5-dione in combination with sorafenib, sunitinib or erlotinib |
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A composition comprising (-)-trans-3-(5,6-dihydro-4h-pyrrolo [3,2,1-ij] quinolin-1-yl)-4-(1h-indol-3-yl) pyrrolidine-2, 5-dione in combination with sorafenib, sunitinib or erlotinib |