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Legal status
Patent not validated
| (51) | INT.CL. | C12Q 1/68 | |
| A61K 31/4184 | |||
| C12N 9/12 |
| (11) | Number of the document | 2545187 |
| (13) | Kind of document | T |
| (96) | European patent application number | 11709278.3 |
| Date of filing the European patent application | 2011-03-09 | |
| (97) | Date of publication of the European application | 2013-01-16 |
| (45) | Date of publication and mention of the grant of the patent | 2018-09-05 |
| (46) | Date of publication of the claims translation |
| (86) | Number | PCT/US2011/027689 |
| Date | 2011-03-09 |
| (87) | Number | WO 2011/112678 |
| Date | 2011-09-15 |
| (30) | Number | Date | Country code |
| 326021 P | 2010-04-20 | US | |
| 312519 P | 2010-03-10 | US | |
| 312193 P | 2010-03-09 | US | |
| 415569 P | 2010-11-19 | US |
| (72) |
GARRAWAY, Levi, A., US
JOHANNESSEN, Cory, M., US
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| (73) |
The Broad Institute, Inc.,
7 Cambridge Center, Cambridge, MA 02142,
US
Dana-Farber Cancer Institute, Inc., 450 Brookline Avenue, Boston, MA 02215, US |
| (54) | METHODS OF DIAGNOSING AND TREATING CANCER IN PATIENTS HAVING OR DEVELOPING RESISTANCE TO A FIRST CANCER THERAPY |
| METHODS OF DIAGNOSING AND TREATING CANCER IN PATIENTS HAVING OR DEVELOPING RESISTANCE TO A FIRST CANCER THERAPY |