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LT - SIRNA THERAPY FOR TRANSTHYRETIN (TTR) RELATED OCULAR AMYLOIDOSIS
EN - SIRNA THERAPY FOR TRANSTHYRETIN (TTR) RELATED OCULAR AMYLOIDOSIS

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Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. A61K 31/7088
C07H 21/02
A61K 48/00
A61K 31/7115
A61K 31/713
C12N 15/113
A61P 27/02
European patent
(11) Number of the document 2552456
(13) Kind of document T
(96) European patent application number 11763336.2
Date of filing the European patent application 2011-03-29
(97) Date of publication of the European application 2013-02-06
(45) Date of publication and mention of the grant of the patent 2017-08-23
(46) Date of publication of the claims translation
PCT application
(86) Number PCT/US2011/030392
Date 2011-03-29
PCT application publication
(87) Number WO 2011/123468
Date 2011-10-06
Priority applications
(30) Number Date Country code
318702 P 2010-03-29 US
318704 P 2010-03-29 US
Inventors
(72)
ANDO, Yukio, JP
JONO, Hirofumi, JP
ALVAREZ, Rene, US
SAH, Dinah, Wen-Yee, US
Grantee
(73) Alnylam Pharmaceuticals, Inc., 300 Third Street, 3rd Floor, Cambridge, MA 02142, US
Kumamoto University, 39-1 Kurokami 2-chome, Kumamoto-shi Kumamoto 860-8555, JP
Ando, Yukio, Alnylam Pharmaceuticals Inc. 300 Third Street Third Floor, Cambridge, MA 02142, US
Jono, Hirofumi, Alnylam Pharmaceuticals Inc. 300 Third Street Third Floor, Cambridge, MA 02142, US
Title
(54) SIRNA THERAPY FOR TRANSTHYRETIN (TTR) RELATED OCULAR AMYLOIDOSIS
  SIRNA THERAPY FOR TRANSTHYRETIN (TTR) RELATED OCULAR AMYLOIDOSIS