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LT - A MEK 1 MUTATION CONFERRING RESISTANCE TO RAF AND MEK INHIBITORS
EN - A MEK 1 MUTATION CONFERRING RESISTANCE TO RAF AND MEK INHIBITORS

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Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C12Q 1/68
C12N 9/12
G01N 33/574
European patent
(11) Number of the document 2580322
(13) Kind of document T
(96) European patent application number 11735711.1
Date of filing the European patent application 2011-06-09
(97) Date of publication of the European application 2013-04-17
(45) Date of publication and mention of the grant of the patent 2018-01-10
(46) Date of publication of the claims translation
PCT application
(86) Number PCT/US2011/039789
Date 2011-06-09
PCT application publication
(87) Number WO 2011/156588
Date 2011-12-15
Priority applications
(30) Number Date Country code
352959 P 2010-06-09 US
Inventors
(72)
GARRAWAY, Levi, A., US
EMERY, Caroline, US
WAGLE, Nikhil, US
Grantee
(73) Dana-Farber Cancer Institute, Inc., 450 Brookline Avenue, Boston, MA 02215, US
Title
(54) A MEK 1 MUTATION CONFERRING RESISTANCE TO RAF AND MEK INHIBITORS
  A MEK 1 MUTATION CONFERRING RESISTANCE TO RAF AND MEK INHIBITORS
Last update date 2021-04-30