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LT - (7S)-1-(3,4-dimetoksibiciklo[4.2.0]okta-1,3,5-trien-7-il) N-metilmetanamino fermentinės sintezės būdas ir panaudojimas ivabradino ir jo druskų sintezei
EN - Method for enzymatic synthesis of (7S)-1-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-yl) N-methyl methanamine, and use for the synthesis of Ivabradine and the salts thereof

Legal status

Patent lapsed (non-payment of fees)

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07C 269/04 (2006.01)
C12P 41/00 (2006.01)
C07D 223/16 (2006.01)
European patent
(11) Number of the document 2687506
(13) Kind of document T
(96) European patent application number 13176588.5
Date of filing the European patent application 2013-07-16
(97) Date of publication of the European application 2014-01-22
(45) Date of publication and mention of the grant of the patent 2015-06-24
(46) Date of publication of the claims translation 2015-08-25
Priority applications
(30) Number Date Country code
1256913 2012-07-17 FR
Inventors
(72)
Pedragosa Moreau, Sandrine, FR
Lefoulon, Francois, FR
Moris Varas, Francisco, ES
Gonzalez Sabin, Javier, ES
Grantee
(73) Les Laboratoires Servier, 35, rue de Verdun, 92284 Suresnes Cedex, FR
Attorney or representative
(74) Stanislava TELEIŠIENĖ, UAB "Brainera", Taikos 235-17, LT-05213 Vilnius, LT
Title
(54) (7S)-1-(3,4-dimetoksibiciklo[4.2.0]okta-1,3,5-trien-7-il) N-metilmetanamino fermentinės sintezės būdas ir panaudojimas ivabradino ir jo druskų sintezei
  Method for enzymatic synthesis of (7S)-1-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-yl) N-methyl methanamine, and use for the synthesis of Ivabradine and the salts thereof
Last renewal fee
Payment date Validity (years) Amount
2018-05-25 6 139.00 EUR
Legal status
Patent lapsed (non-payment of fees)
Invalidation date 2019-07-16