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Legal status
Patent not validated
(51) | INT.CL. | C07D 413/14 | |
C07D 403/04 | |||
C07D 417/14 | |||
A61K 31/4155 | |||
A61P 43/00 |
(11) | Number of the document | 2797915 |
(13) | Kind of document | T |
(96) | European patent application number | 12812498.9 |
Date of filing the European patent application | 2012-12-26 | |
(97) | Date of publication of the European application | 2014-11-05 |
(45) | Date of publication and mention of the grant of the patent | 2016-07-13 |
(46) | Date of publication of the claims translation |
(86) | Number | PCT/US2012/071654 |
Date | 2012-12-26 |
(87) | Number | WO 2013/101830 |
Date | 2013-07-04 |
(30) | Number | Date | Country code |
201161580439 P | 2011-12-27 | US | |
201261654580 P | 2012-06-01 | US |
(72) |
KIM, Charles, US
NAKAI, Takashi, US
MOORE, Joel, US
PERL, Nicholas, Robert, US
IM, G-yoon, Jamie, US
BARDEN, Timothy, Claude, US
IYENGAR, Rajesh, R., US
ZIMMER, Daniel, P., US
FRETZEN, Angelika, US
RENHOWE, Paul, Allan, US
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(73) |
Ironwood Pharmaceuticals, Inc.,
301 Binney Street, 2nd Floor, Cambridge, MA 02142,
US
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(54) | 2-benzyl-3-(oxazole/thiazole)-5-(pyrimidin-2-yl)-1(H)-pyrazole derivatives as stimulators of the soluble guanylate cyclase (sGC) for the treatment of e.g. hypertension or heart failure |
2-benzyl-3-(oxazole/thiazole)-5-(pyrimidin-2-yl)-1(H)-pyrazole derivatives as stimulators of the soluble guanylate cyclase (sGC) for the treatment of e.g. hypertension or heart failure |