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LT - METHODS FOR TREATING AUTOSOMAL DOMINANT HYPERCHOLESTEROLEMIA ASSOCIATED WITH PCSK9 GAIN-OF-FUNCTION MUTATIONS
EN - METHODS FOR TREATING AUTOSOMAL DOMINANT HYPERCHOLESTEROLEMIA ASSOCIATED WITH PCSK9 GAIN-OF-FUNCTION MUTATIONS

Legal status

Patent not validated

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07K 16/40
C12Q 1/68
A61K 39/00
C12Q 1/6883
European patent
(11) Number of the document 3004172
(13) Kind of document T
(96) European patent application number 14739600.6
Date of filing the European patent application 2014-05-29
(97) Date of publication of the European application 2016-04-13
(45) Date of publication and mention of the grant of the patent 2019-11-27
(46) Date of publication of the claims translation
PCT application
(86) Number PCT/US2014/040050
Date 2014-05-29
PCT application publication
(87) Number WO 2014/194111
Date 2014-12-04
Priority applications
(30) Number Date Country code
201361828730 P 2013-05-30 US
201361889553 P 2013-10-11 US
201361901212 P 2013-11-07 US
Inventors
(72)
SWERGOLD, Gary, US
MELLIS, Scott, US
SASIELA, William, J., US
Grantee
(73) Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, US
Title
(54) METHODS FOR TREATING AUTOSOMAL DOMINANT HYPERCHOLESTEROLEMIA ASSOCIATED WITH PCSK9 GAIN-OF-FUNCTION MUTATIONS
  METHODS FOR TREATING AUTOSOMAL DOMINANT HYPERCHOLESTEROLEMIA ASSOCIATED WITH PCSK9 GAIN-OF-FUNCTION MUTATIONS