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(51) | INT.CL. | C12N 15/63 | |
C12N 15/10 | |||
C40B 40/08 | |||
C12N 9/22 |
(11) | Number of the document | 3011031 |
(13) | Kind of document | T |
(96) | European patent application number | 14734710.8 |
Date of filing the European patent application | 2014-06-10 | |
(97) | Date of publication of the European application | 2016-04-27 |
(45) | Date of publication and mention of the grant of the patent | 2020-09-30 |
(46) | Date of publication of the claims translation |
(86) | Number | PCT/US2014/041804 |
Date | 2014-06-10 |
(87) | Number | WO 2014/204726 |
Date | 2014-12-24 |
(30) | Number | Date | Country code |
201361836123 P | 2013-06-17 | US | |
201361847537 P | 2013-07-17 | US | |
201361862355 P | 2013-08-05 | US | |
201361871301 P | 2013-08-28 | US | |
PCT/US2013/0746 | 2013-12-12 | WO | |
201361915325 P | 2013-12-12 | US | |
201461979733 P | 2014-04-15 | US |
(72) |
ZHANG, Feng, US
CONG, Le, US
RAN, Fei, US
|
(73) |
President and Fellows of Harvard College,
17 Quincy Street, Cambridge, MA 02138,
US
Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02142, US The Broad Institute Inc., 415 Main Street, Cambridge, MA 02142, US |
(54) | DELIVERY AND USE OF THE CRISPR-CAS SYSTEMS, VECTORS AND COMPOSITIONS FOR HEPATIC TARGETING AND THERAPY |
DELIVERY AND USE OF THE CRISPR-CAS SYSTEMS, VECTORS AND COMPOSITIONS FOR HEPATIC TARGETING AND THERAPY |