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EN - OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION

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Patent not validated

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. A61K 47/54 (2017.01)
C07H 21/00 (2013.01)
C07H 21/00 (2006.01)
C12N 15/111 (2013.01)
A61P 1/16 (2006.01)
C12N2310/14 (2013.01)
C12N2310/351 (2013.01)
C12N2320/32 (2013.01)
C12N2330/30 (2013.01)
A61K 47/549 (2017.08)
A61P 1/16 (2018.01)
A61P 43/00 (2018.01)
European patent
(11) Number of the document 3019200
(13) Kind of document T
(96) European patent application number 14744737.9
Date of filing the European patent application 2014-07-11
(97) Date of publication of the European application 2016-05-18
(45) Date of publication and mention of the grant of the patent 2022-03-23
(46) Date of publication of the claims translation
PCT application
(86) Number PCT/US2014/046425
Date 2014-07-11
PCT application publication
(87) Number WO 2015/006740
Date 2015-01-15
Priority applications
(30) Number Date Country code
201361845279 P 2013-07-11 US
Inventors
(72)
MANOHARAN, Muthiah , US
NAIR, Jayaprakash, K. , US
KANDASAMY, Pachamuthu , US
MATSUDA, Shigeo , US
KELIN, Alexander, V. , US
JAYARAMAN, Muthusamy , US
RAJEEV, Kallanthottathil, G. , US
Grantee
(73) Alnylam Pharmaceuticals, Inc. , 300 Third Street, Cambridge, MA 02142, US
Title
(54) OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION
  OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION