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LT - IMPROVED HIV-1-NEUTRALIZING ANTIBODY POTENCY AND BREADTH VIA CELL RECEPTOR ANCHORING USING BISPECIFIC ANTIBODIES WITH NATIVE ARCHITECTURE
EN - IMPROVED HIV-1-NEUTRALIZING ANTIBODY POTENCY AND BREADTH VIA CELL RECEPTOR ANCHORING USING BISPECIFIC ANTIBODIES WITH NATIVE ARCHITECTURE

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Patent not validated

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. A61P 31/18 (2006.01)
C07K2317/24 (2013.01)
A61K 39/42 (2006.01)
C07K2317/94 (2013.01)
C07K 16/46 (2006.01)
C07K 16/1063 (2013.01)
C07K 16/10 (2006.01)
C07K 16/2812 (2013.01)
C07K 16/28 (2006.01)
C07K 16/2866 (2013.01)
C07K2317/76 (2013.01)
C07K2317/31 (2013.01)
A61P 31/18 (2018.01)
European patent
(11) Number of the document 3077051
(13) Kind of document T
(96) European patent application number 14867086.2
Date of filing the European patent application 2014-12-02
(97) Date of publication of the European application 2016-10-12
(45) Date of publication and mention of the grant of the patent 2023-04-12
(46) Date of publication of the claims translation
PCT application
(86) Number PCT/US2014/068183
Date 2014-12-02
PCT application publication
(87) Number WO 2015/084859
Date 2015-06-11
Priority applications
(30) Number Date Country code
201361910685 P 2013-12-02 US
Inventors
(72)
HO, David, D. , US
HUANG, Yaoxing , US
YU, Jian , US
Grantee
(73) The Trustees of Columbia University in the City of New York , Office of the General Counsel 412 Low Memorial Library 535 West 116th St. MC 4308, New York, NY 10027, US
Title
(54) IMPROVED HIV-1-NEUTRALIZING ANTIBODY POTENCY AND BREADTH VIA CELL RECEPTOR ANCHORING USING BISPECIFIC ANTIBODIES WITH NATIVE ARCHITECTURE
  IMPROVED HIV-1-NEUTRALIZING ANTIBODY POTENCY AND BREADTH VIA CELL RECEPTOR ANCHORING USING BISPECIFIC ANTIBODIES WITH NATIVE ARCHITECTURE