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Legal status
Patent not validated
| (51) | INT.CL. | C07D 487/04 | |
| A61K 31/5517 | |||
| A61P 25/00 |
| (11) | Number of the document | 3077396 |
| (13) | Kind of document | T |
| (96) | European patent application number | 14805290.5 |
| Date of filing the European patent application | 2014-12-01 | |
| (97) | Date of publication of the European application | 2016-10-12 |
| (45) | Date of publication and mention of the grant of the patent | 2021-04-21 |
| (46) | Date of publication of the claims translation |
| (86) | Number | PCT/EP2014/076041 |
| Date | 2014-12-01 |
| (87) | Number | WO 2015/082370 |
| Date | 2015-06-11 |
| (30) | Number | Date | Country code |
| 13195864 | 2013-12-05 | EP |
| (72) |
ROTHENHAEUSLER, Benno, DE
TRUSSARDI, René, CH
HOFFMANN-EMERY, Fabienne, DE
SCHWITTER, Urs, CH
ADAM, Jean-Michel, FR
GRASSMANN, Olaf, DE
HARTUNG, Thomas, DE
RAN, Frederic, FR
DIODONE, Ralph, DE
PFLEGER, Christophe, FR
BARTELS, Bjoern, DE
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| (73) |
F. Hoffmann-La Roche AG,
Grenzacher Strasse 124, 4070 Basel,
CH
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| (54) | SYNTHESIS OF TRANS-8-CHLORO-5-METHYL-1 -[4-(PYRIDIN-2-YLOXY)-CYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENE AND CRYTALLINE FORMS THEREOF |
| SYNTHESIS OF TRANS-8-CHLORO-5-METHYL-1 -[4-(PYRIDIN-2-YLOXY)-CYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENE AND CRYTALLINE FORMS THEREOF |