Patent details

EN | LT

LT - PROCESS FOR THE MANUFACTURE OF (E)-4-N,N-DIALKYLAMINO CROTONIC ACID IN HX SALT FORM AND USE THEREOF FOR SYNTHESIS OF EGFR TYROSINE KINASE INHIBITORS

EN - PROCESS FOR THE MANUFACTURE OF (E)-4-N,N-DIALKYLAMINO CROTONIC ACID IN HX SALT FORM AND USE THEREOF FOR SYNTHESIS OF EGFR TYROSINE KINASE INHIBITORS

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Bibliographic data

Indications of the International Patent Classification (IPC)
(51)	INT.CL.	C07C 227/10
		C07C 227/18
		C07C 229/30
		C07D 405/04

European patent
(11)	Number of the document	3089961
(13)	Kind of document	T
(96)	European patent application number	14828037.3
	Date of filing the European patent application	2014-12-23
(97)	Date of publication of the European application	2016-11-09
(45)	Date of publication and mention of the grant of the patent	2018-07-11
(46)	Date of publication of the claims translation

PCT application
(86)	Number	PCT/EP2014/079150
	Date	2014-12-23

PCT application publication
(87)	Number	WO 2015/101554
	Date	2015-07-09

Priority applications
(30)	Number	Date	Country code
	PCT/CN2013/0910	2013-12-31	WO

Inventors
(72)	ZHENG, Juncheng, CN DENG, Da, CN LV, Guanghua, CN YAN, Jun, CN BRANDENBURG, Joerg, DE KROEBER, Jutta, DE SCHOLZ, Ulrich, DE

Grantee
(73)	Boehringer Ingelheim International GmbH, Binger Strasse 173, 55216 Ingelheim am Rhein, DE

Title
(54)	PROCESS FOR THE MANUFACTURE OF (E)-4-N,N-DIALKYLAMINO CROTONIC ACID IN HX SALT FORM AND USE THEREOF FOR SYNTHESIS OF EGFR TYROSINE KINASE INHIBITORS
	PROCESS FOR THE MANUFACTURE OF (E)-4-N,N-DIALKYLAMINO CROTONIC ACID IN HX SALT FORM AND USE THEREOF FOR SYNTHESIS OF EGFR TYROSINE KINASE INHIBITORS