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LT - N-(5-((ARYL OR HETEROARYL)METHYLOXY)PENTYL)-SUBSTITUTED IMINOSUGARS AS INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE
EN - N-(5-((ARYL OR HETEROARYL)METHYLOXY)PENTYL)-SUBSTITUTED IMINOSUGARS AS INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE

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Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07D 211/46
C07D 401/12
C07D 405/12
A61K 31/445
A61K 31/4545
A61P 3/00
A61P 25/16
A61P 9/10
European patent
(11) Number of the document 3122726
(13) Kind of document T
(96) European patent application number 15719845.8
Date of filing the European patent application 2015-03-23
(97) Date of publication of the European application 2017-02-01
(45) Date of publication and mention of the grant of the patent 2018-08-29
(46) Date of publication of the claims translation
PCT application
(86) Number PCT/NL2015/050188
Date 2015-03-23
PCT application publication
(87) Number WO 2015/147639
Date 2015-10-01
Priority applications
(30) Number Date Country code
14162104 2014-03-27 EP
Inventors
(72)
OVERKLEEFT, Herman Steven, NL
VAN BOECKEL, Stan, NL
AERTS, Johannes Maria Franciscus Gerardus, NL
GHISAIDOOBE, Amar, NL
VAN DEN BERG, Richard, NL
Grantee
(73) Universiteit Leiden, Rapenburg 70, 2311 EZ Leiden, NL
Academisch Medisch Centrum, Meibergdreef 9, 1105 AZ Amsterdam Zuidoost, NL
Title
(54) N-(5-((ARYL OR HETEROARYL)METHYLOXY)PENTYL)-SUBSTITUTED IMINOSUGARS AS INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE
  N-(5-((ARYL OR HETEROARYL)METHYLOXY)PENTYL)-SUBSTITUTED IMINOSUGARS AS INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE