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Legal status
Patent not validated
| (51) | INT.CL. | C07H 21/00 | |
| C12N 15/113 | |||
| A61K 31/7088 | |||
| A61K 31/7125 |
| (11) | Number of the document | 3137091 |
| (13) | Kind of document | T |
| (96) | European patent application number | 15786489.3 |
| Date of filing the European patent application | 2015-05-01 | |
| (97) | Date of publication of the European application | 2017-03-08 |
| (45) | Date of publication and mention of the grant of the patent | 2020-12-02 |
| (46) | Date of publication of the claims translation |
| (86) | Number | PCT/US2015/028765 |
| Date | 2015-05-01 |
| (87) | Number | WO 2015/168532 |
| Date | 2015-11-05 |
| (30) | Number | Date | Country code |
| 201461987478 P | 2014-05-01 | US | |
| 201462058629 P | 2014-10-01 | US | |
| 201462088459 P | 2014-12-05 | US |
| (72) |
PRAKASH, Thazha P., US
SETH, Punit P., US
SWAYZE, Eric E., US
FREIER, Susan M., US
BUI, Huynh-Hoa, US
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| (73) |
Ionis Pharmaceuticals, Inc.,
2855 Gazelle Court, Carlsbad, CA 92010,
US
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| (54) | CONJUGATES OF MODIFIED ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR MODULATING PKK EXPRESSION |
| CONJUGATES OF MODIFIED ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR MODULATING PKK EXPRESSION |