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(51) | INT.CL. | C12N 15/63 | |
C12N 15/10 |
(11) | Number of the document | 3144390 |
(13) | Kind of document | T |
(96) | European patent application number | 16194919.3 |
Date of filing the European patent application | 2013-12-12 | |
(97) | Date of publication of the European application | 2017-03-22 |
(45) | Date of publication and mention of the grant of the patent | 2020-03-18 |
(46) | Date of publication of the claims translation |
(30) | Number | Date | Country code |
201261736527 P | 2012-12-12 | US | |
201361748427 P | 2013-01-02 | US | |
201361758468 P | 2013-01-30 | US | |
201361769046 P | 2013-02-25 | US | |
201361791409 P | 2013-03-15 | US | |
201361802174 P | 2013-03-15 | US | |
201361806375 P | 2013-03-28 | US | |
201361814263 P | 2013-04-20 | US | |
201361819803 P | 2013-05-06 | US | |
201361828130 P | 2013-05-28 | US | |
201361835931 P | 2013-06-17 | US | |
201361836127 P | 2013-06-17 | US |
(72) |
ZHANG, Feng, US
HSU, Patrick, US
CONG, Le, US
RAN, Fei, US
|
(73) |
Massachusetts Institute of Technology,
77 Massachusetts Avenue, Cambridge, MA 02142-1324,
US
President and Fellows of Harvard College, 17 Quincy Street, Cambridge, MA 02138-3876, US The Broad Institute, Inc., 415 Main Street, Cambridge, MA 02142, US |
(54) | ENGINEERING OF SYSTEMS, METHODS AND OPTIMIZED GUIDE COMPOSITIONS FOR SEQUENCE MANIPULATION |
ENGINEERING OF SYSTEMS, METHODS AND OPTIMIZED GUIDE COMPOSITIONS FOR SEQUENCE MANIPULATION |