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Legal status
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(51) | INT.CL. | A61K 31/517 | (2006.01) |
A61K 31/404 | (2013.01) | ||
A61K 31/416 | (2006.01) | ||
A61K 45/06 | (2013.01) | ||
A61K 31/404 | (2006.01) | ||
A61K 31/337 | (2013.01) | ||
A61K 31/136 | (2006.01) | ||
A61K 31/7048 | (2013.01) | ||
A61K 31/66 | (2006.01) | ||
A61K 31/7068 | (2013.01) | ||
A61K 31/198 | (2006.01) | ||
A61P 35/00 | (2018.01) | ||
A61P 35/00 | (2006.01) | ||
A61K 31/4439 | (2013.01) |
(11) | Number of the document | 3217983 |
(13) | Kind of document | T |
(96) | European patent application number | 15859462.2 |
Date of filing the European patent application | 2015-11-12 | |
(97) | Date of publication of the European application | 2017-09-20 |
(45) | Date of publication and mention of the grant of the patent | 2024-05-01 |
(46) | Date of publication of the claims translation |
(86) | Number | PCT/US2015/060486 |
Date | 2015-11-12 |
(87) | Number | WO 2016/077652 |
Date | 2016-05-19 |
(30) | Number | Date | Country code |
201462078280 P | 2014-11-11 | US |
(72) |
KOLESNICK, Richard , US
HAIMOVITZ-FRIEDMAN, Adriana , US
SALA, Evis , US
FUKS, Zvi , US
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(73) |
Memorial Sloan Kettering Cancer Center ,
1275 York Avenue, New York, NY 10021,
US
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(54) | ENHANCEMENT OF TUMOR RESPONSE TO CHEMOTHERAPY BY ACTIVATION OF THE ASMASE/CERAMIDE PATHWAY THROUGH TIMED ADMINISTRATION OF A SHORT-ACTING ANTI-ANGIOGENIC AGENT |
ENHANCEMENT OF TUMOR RESPONSE TO CHEMOTHERAPY BY ACTIVATION OF THE ASMASE/CERAMIDE PATHWAY THROUGH TIMED ADMINISTRATION OF A SHORT-ACTING ANTI-ANGIOGENIC AGENT |