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LT - PREPARATION OF A CRYSTALLINE FORM OF (S)-N-(5-((R)-2-(2,5-DIFLUOROPHENYL)-PYRROLIDIN-1-YL)-PYRAZOLO[1,5-A]PYRIMIDIN-3-YL)-3-HYDROXYPYRROLIDINE-1-CARBOXAMIDE HYDROGEN SULFATE
EN - PREPARATION OF A CRYSTALLINE FORM OF (S)-N-(5-((R)-2-(2,5-DIFLUOROPHENYL)-PYRROLIDIN-1-YL)-PYRAZOLO[1,5-A]PYRIMIDIN-3-YL)-3-HYDROXYPYRROLIDINE-1-CARBOXAMIDE HYDROGEN SULFATE

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Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07D 487/04
A61K 31/519
A61P 35/00
European patent
(11) Number of the document 3218380
(13) Kind of document T
(96) European patent application number 15808300.6
Date of filing the European patent application 2015-11-16
(97) Date of publication of the European application 2017-09-20
(45) Date of publication and mention of the grant of the patent 2021-03-17
(46) Date of publication of the claims translation
PCT application
(86) Number PCT/US2015/060953
Date 2015-11-16
PCT application publication
(87) Number WO 2016/077841
Date 2016-05-19
Priority applications
(30) Number Date Country code
201462080374 P 2014-11-16 US
201562169545 P 2015-06-01 US
Inventors
(72)
ARRIGO, Alisha B., US
JUENGST, Derrick, US
SHAH, Khalid, US
Grantee
(73) Array Biopharma, Inc., 3200 Walnut Street, Boulder, CO 80301, US
Title
(54) PREPARATION OF A CRYSTALLINE FORM OF (S)-N-(5-((R)-2-(2,5-DIFLUOROPHENYL)-PYRROLIDIN-1-YL)-PYRAZOLO[1,5-A]PYRIMIDIN-3-YL)-3-HYDROXYPYRROLIDINE-1-CARBOXAMIDE HYDROGEN SULFATE
  PREPARATION OF A CRYSTALLINE FORM OF (S)-N-(5-((R)-2-(2,5-DIFLUOROPHENYL)-PYRROLIDIN-1-YL)-PYRAZOLO[1,5-A]PYRIMIDIN-3-YL)-3-HYDROXYPYRROLIDINE-1-CARBOXAMIDE HYDROGEN SULFATE