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(51) | INT.CL. | C07K 16/2818 | (2013.01) |
C40B 30/04 | (2006.01) | ||
A61K 39/00 | (2006.01) | ||
A61K2039/505 | (2013.01) | ||
A61K 39/395 | (2006.01) | ||
C07K2317/24 | (2013.01) | ||
C07K2317/76 | (2013.01) | ||
C12Q 1/68 | (2013.01) | ||
C12Q2600/106 | (2013.01) | ||
C12Q2600/158 | (2013.01) | ||
G16B 20/00 | (2019.02) | ||
G16B 30/00 | (2019.02) | ||
G16B 40/00 | (2019.02) | ||
C12Q 1/6886 | (2013.01) | ||
A61P 35/00 | (2018.01) | ||
A61P 43/00 | (2018.01) | ||
G16B 40/30 | (2019.02) | ||
G16B 20/20 | (2019.02) |
(11) | Number of the document | 3230498 |
(13) | Kind of document | T |
(96) | European patent application number | 15868101.5 |
Date of filing the European patent application | 2015-12-08 | |
(97) | Date of publication of the European application | 2017-10-18 |
(45) | Date of publication and mention of the grant of the patent | 2023-01-18 |
(46) | Date of publication of the claims translation |
(86) | Number | PCT/US2015/064445 |
Date | 2015-12-08 |
(87) | Number | WO 2016/094377 |
Date | 2016-06-16 |
(30) | Number | Date | Country code |
201462089538 P | 2014-12-09 | US | |
201562160284 P | 2015-05-12 | US |
(72) |
AYERS, Mark, D. , US
LOBODA, Andrey , US
LUNCEFORD, Jared, K. , US
MCCLANAHAN, Terrill, K. , US
MURPHY, Erin, E. , US
NEBOZHYN, Michael , US
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(73) |
Merck Sharp & Dohme LLC ,
126 East Lincoln Avenue, Rahway, New Jersey 07065,
US
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(54) | SYSTEM AND METHODS FOR DERIVING GENE SIGNATURE BIOMARKERS OF RESPONSE TO PD-1 ANTAGONISTS |
SYSTEM AND METHODS FOR DERIVING GENE SIGNATURE BIOMARKERS OF RESPONSE TO PD-1 ANTAGONISTS |