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LT - SYSTEM AND METHODS FOR DERIVING GENE SIGNATURE BIOMARKERS OF RESPONSE TO PD-1 ANTAGONISTS
EN - SYSTEM AND METHODS FOR DERIVING GENE SIGNATURE BIOMARKERS OF RESPONSE TO PD-1 ANTAGONISTS

Legal status

Patent not validated

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07K 16/2818 (2013.01)
C40B 30/04 (2006.01)
A61K 39/00 (2006.01)
A61K2039/505 (2013.01)
A61K 39/395 (2006.01)
C07K2317/24 (2013.01)
C07K2317/76 (2013.01)
C12Q 1/68 (2013.01)
C12Q2600/106 (2013.01)
C12Q2600/158 (2013.01)
G16B 20/00 (2019.02)
G16B 30/00 (2019.02)
G16B 40/00 (2019.02)
C12Q 1/6886 (2013.01)
A61P 35/00 (2018.01)
A61P 43/00 (2018.01)
G16B 40/30 (2019.02)
G16B 20/20 (2019.02)
European patent
(11) Number of the document 3230498
(13) Kind of document T
(96) European patent application number 15868101.5
Date of filing the European patent application 2015-12-08
(97) Date of publication of the European application 2017-10-18
(45) Date of publication and mention of the grant of the patent 2023-01-18
(46) Date of publication of the claims translation
PCT application
(86) Number PCT/US2015/064445
Date 2015-12-08
PCT application publication
(87) Number WO 2016/094377
Date 2016-06-16
Priority applications
(30) Number Date Country code
201462089538 P 2014-12-09 US
201562160284 P 2015-05-12 US
Inventors
(72)
AYERS, Mark, D. , US
LOBODA, Andrey , US
LUNCEFORD, Jared, K. , US
MCCLANAHAN, Terrill, K. , US
MURPHY, Erin, E. , US
NEBOZHYN, Michael , US
Grantee
(73) Merck Sharp & Dohme LLC , 126 East Lincoln Avenue, Rahway, New Jersey 07065, US
Title
(54) SYSTEM AND METHODS FOR DERIVING GENE SIGNATURE BIOMARKERS OF RESPONSE TO PD-1 ANTAGONISTS
  SYSTEM AND METHODS FOR DERIVING GENE SIGNATURE BIOMARKERS OF RESPONSE TO PD-1 ANTAGONISTS