|
|
|
|
|
Legal status
Patent not validated
| (51) | INT.CL. | C07K 16/00 | (2006.01) |
| C07K 16/00 | (2013.01) | ||
| A01K 67/027 | (2006.01) | ||
| C07K 16/1054 | (2013.01) | ||
| C07K 16/1063 | (2013.01) | ||
| C12N 5/10 | (2006.01) | ||
| C07K 16/1232 | (2013.01) | ||
| C07K2317/22 | (2013.01) | ||
| C07K2317/31 | (2013.01) | ||
| C07K2317/53 | (2013.01) | ||
| C07K2317/569 | (2013.01) | ||
| C07K2319/00 | (2013.01) | ||
| C07K2317/64 | (2013.01) | ||
| C07K 16/241 | (2013.01) | ||
| A61P 1/00 | (2018.01) | ||
| A61P 11/06 | (2018.01) | ||
| A61P 13/12 | (2018.01) | ||
| A61P 15/00 | (2018.01) | ||
| A61P 17/06 | (2018.01) | ||
| A61P 19/02 | (2018.01) | ||
| A61P 19/10 | (2018.01) | ||
| A61P 25/00 | (2018.01) | ||
| A61P 25/28 | (2018.01) | ||
| A61P 31/04 | (2018.01) | ||
| A61P 31/12 | (2018.01) | ||
| A61P 31/18 | (2018.01) | ||
| A61P 33/00 | (2018.01) | ||
| A61P 35/00 | (2018.01) | ||
| A61P 35/02 | (2018.01) | ||
| A61P 3/04 | (2018.01) | ||
| A61P 37/00 | (2018.01) | ||
| A61P 37/02 | (2018.01) | ||
| A61P 37/04 | (2018.01) | ||
| A61P 37/06 | (2018.01) | ||
| A61P 7/02 | (2018.01) | ||
| A61P 9/00 | (2018.01) | ||
| A61P 9/10 | (2018.01) | ||
| A61P 9/12 | (2018.01) | ||
| A61P 3/10 | (2018.01) | ||
| C07K 16/30 | (2013.01) | ||
| C07K2319/73 | (2013.01) |
| (11) | Number of the document | 3272770 |
| (13) | Kind of document | T |
| (96) | European patent application number | 17173113.6 |
| Date of filing the European patent application | 2005-07-22 | |
| (97) | Date of publication of the European application | 2018-01-24 |
| (45) | Date of publication and mention of the grant of the patent | 2023-12-20 |
| (46) | Date of publication of the claims translation |
| (30) | Number | Date | Country code |
| 0416392 | 2004-07-22 | GB | |
| 0511881 | 2005-06-10 | GB |
| (72) |
GROSVELD, Franklin G. , NL
JANSSENS, Richard W. , NL
DRABEK, Dubravka , NL
CRAIG, Roger Kingdon , GB
|
| (73) |
Erasmus University Medical
Center Rotterdam ,
P.O.Box 1738, 3000 DR Rotterdam,
NL
Craig, Roger Kingdon , Jubilee House Farm, Spen Moss, Smallwood Sandbach, Cheshire CW11 2XB, GB |
| (54) | METHOD FOR THE PRODUCTION OF A VH HEAVY CHAIN-ONLY ANTIBODY IN A TRANSGENIC MAMMAL AND BINDING POLYPEPTIDE COMPLEX CONSISTING OF A DIMER OF A FIRST CHAIN AND A SECOND CHAIN WHEREIN EACH CHAIN CONSISTS OF TWO ANTIGEN-SPECIFIC VH BINDING DOMAINS LINKED BY A DIMERISATION DOMAIN |
| METHOD FOR THE PRODUCTION OF A VH HEAVY CHAIN-ONLY ANTIBODY IN A TRANSGENIC MAMMAL AND BINDING POLYPEPTIDE COMPLEX CONSISTING OF A DIMER OF A FIRST CHAIN AND A SECOND CHAIN WHEREIN EACH CHAIN CONSISTS OF TWO ANTIGEN-SPECIFIC VH BINDING DOMAINS LINKED BY A DIMERISATION DOMAIN |