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LT - A METHOD FOR PREPARING METHYL (Z)-3-[[4-[METHYL[2-(4-METHYL-1-PIPERAZINYL)ACETYL]AMINO]PHENYL]AMINO]PHENYLMETHYLENE)-OXINDOLE-6-CARBOXYLATE (INTEDANIB, NINTEDANIB)
EN - A METHOD FOR PREPARING METHYL (Z)-3-[[4-[METHYL[2-(4-METHYL-1-PIPERAZINYL)ACETYL]AMINO]PHENYL]AMINO]PHENYLMETHYLENE)-OXINDOLE-6-CARBOXYLATE (INTEDANIB, NINTEDANIB)

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Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07D 209/34
European patent
(11) Number of the document 3328831
(13) Kind of document T
(96) European patent application number 16753813.1
Date of filing the European patent application 2016-07-28
(97) Date of publication of the European application 2018-06-06
(45) Date of publication and mention of the grant of the patent 2020-07-29
(46) Date of publication of the claims translation
PCT application
(86) Number PCT/CZ2016/000083
Date 2016-07-28
PCT application publication
(87) Number WO 2017/016530
Date 2017-02-02
Priority applications
(30) Number Date Country code
20150527 2015-07-29 CZ
Inventors
(72)
MECA, Ludek, CZ
Grantee
(73) Zentiva, K.S., U Kabelovny 130, 102 37 Praha 10, CZ
Title
(54) A METHOD FOR PREPARING METHYL (Z)-3-[[4-[METHYL[2-(4-METHYL-1-PIPERAZINYL)ACETYL]AMINO]PHENYL]AMINO]PHENYLMETHYLENE)-OXINDOLE-6-CARBOXYLATE (INTEDANIB, NINTEDANIB)
  A METHOD FOR PREPARING METHYL (Z)-3-[[4-[METHYL[2-(4-METHYL-1-PIPERAZINYL)ACETYL]AMINO]PHENYL]AMINO]PHENYLMETHYLENE)-OXINDOLE-6-CARBOXYLATE (INTEDANIB, NINTEDANIB)