LT - A METHOD FOR PREPARING METHYL (Z)-3-[[4-[METHYL[2-(4-METHYL-1-PIPERAZINYL)ACETYL]AMINO]PHENYL]AMINO]PHENYLMETHYLENE)-OXINDOLE-6-CARBOXYLATE (INTEDANIB, NINTEDANIB)
EN - A METHOD FOR PREPARING METHYL (Z)-3-[[4-[METHYL[2-(4-METHYL-1-PIPERAZINYL)ACETYL]AMINO]PHENYL]AMINO]PHENYLMETHYLENE)-OXINDOLE-6-CARBOXYLATE (INTEDANIB, NINTEDANIB)
Legal status
Patent not validated
Bibliographic data
Indications of the International Patent Classification (IPC)
(51) |
INT.CL. |
C07D 209/34 |
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European patent
(11) |
Number of the document |
3328831 |
(13) |
Kind of document |
T |
(96) |
European patent application number |
16753813.1 |
|
Date of filing the European patent application |
2016-07-28 |
(97) |
Date of publication of the European application |
2018-06-06 |
(45) |
Date of publication and mention of the grant of the patent |
2020-07-29
|
(46) |
Date of publication of the claims translation |
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PCT application
(86) |
Number |
PCT/CZ2016/000083 |
|
Date |
2016-07-28 |
PCT application publication
(87) |
Number |
WO 2017/016530 |
|
Date |
2017-02-02 |
Priority applications
(30) |
Number |
Date |
Country code |
|
20150527 |
2015-07-29
|
CZ |
Inventors
(72) |
MECA, Ludek, CZ
|
Grantee
(73) |
Zentiva, K.S.,
U Kabelovny 130, 102 37 Praha 10,
CZ
|
Title
(54) |
A METHOD FOR PREPARING METHYL (Z)-3-[[4-[METHYL[2-(4-METHYL-1-PIPERAZINYL)ACETYL]AMINO]PHENYL]AMINO]PHENYLMETHYLENE)-OXINDOLE-6-CARBOXYLATE (INTEDANIB, NINTEDANIB) |
|
A METHOD FOR PREPARING METHYL (Z)-3-[[4-[METHYL[2-(4-METHYL-1-PIPERAZINYL)ACETYL]AMINO]PHENYL]AMINO]PHENYLMETHYLENE)-OXINDOLE-6-CARBOXYLATE (INTEDANIB, NINTEDANIB) |