LT - Sintezės būdas, skirtas pagaminti (S)-(2R,3R,11bR)-3-izobutil-9,10-dimetoksi-2,3,4,6,7,11b-heksahidro-1H-pirido[2,1-a]izochinolin-2-ilo 2-amino-3-metilbutanoato di(4-metilbenzensulfonatą)
EN - SYNTHETIC METHOD FOR PREPARATION OF (S)-(2R,3R,11BR)-3-ISOBUTYL-9,10-DIMETHOXY-2,3,4,6,7,11B-HEXAHYDRO-1H-PYRIDO[2,1,-A]LSOQUINOLIN-2-YL 2-AMINO-3-METHYLBUTANOATE DI(4-METHYLBENZENESULFONATE)
Legal status
Patent in force
Bibliographic data
Indications of the International Patent Classification (IPC)
| (51) |
INT.CL. |
C07D 471/04 |
(2006.01) |
European patent
| (11) |
Number of the document |
3394057 |
| (13) |
Kind of document |
T |
| (96) |
European patent application number |
16823529.9 |
|
Date of filing the European patent application |
2016-12-22 |
| (97) |
Date of publication of the European application |
2018-10-31 |
| (45) |
Date of publication and mention of the grant of the patent |
2022-03-30
|
| (46) |
Date of publication of the claims translation |
2022-06-27
|
PCT application
| (86) |
Number |
PCT/US2016/068277 |
|
Date |
2016-12-22 |
PCT application publication
| (87) |
Number |
WO 2017/112857 |
|
Date |
2017-06-29 |
Priority applications
| (30) |
Number |
Date |
Country code |
|
201562387442 P |
2015-12-23
|
US |
Inventors
| (72) |
MCGEE, Kevin , US
LI, Bin-Feng , CN
|
Grantee
| (73) |
NEUROCRINE BIOSCIENCES, INC. ,
12780 El Camino Real, San Diego, CA 92130,
US
|
Attorney or representative
| (74) |
Jurga PETNIŪNAITĖ,
AAA Law, A. Goštauto g. 40B, Verslo centras "Dvyniai", LT-03163 Vilnius,
LT
|
Title
| (54) |
Sintezės būdas, skirtas pagaminti (S)-(2R,3R,11bR)-3-izobutil-9,10-dimetoksi-2,3,4,6,7,11b-heksahidro-1H-pirido[2,1-a]izochinolin-2-ilo 2-amino-3-metilbutanoato di(4-metilbenzensulfonatą) |
| |
SYNTHETIC METHOD FOR PREPARATION OF (S)-(2R,3R,11BR)-3-ISOBUTYL-9,10-DIMETHOXY-2,3,4,6,7,11B-HEXAHYDRO-1H-PYRIDO[2,1,-A]LSOQUINOLIN-2-YL 2-AMINO-3-METHYLBUTANOATE DI(4-METHYLBENZENESULFONATE) |
Last renewal fee
|
Payment date |
Validity (years) |
Amount |
|
2025-12-02 |
10 |
231.00
EUR
|
Next renewal fee
|
2026-12-22 |