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LT - Sintezės būdas, skirtas pagaminti (S)-(2R,3R,11bR)-3-izobutil-9,10-dimetoksi-2,3,4,6,7,11b-heksahidro-1H-pirido[2,1-a]izochinolin-2-ilo 2-amino-3-metilbutanoato di(4-metilbenzensulfonatą)
EN - SYNTHETIC METHOD FOR PREPARATION OF (S)-(2R,3R,11BR)-3-ISOBUTYL-9,10-DIMETHOXY-2,3,4,6,7,11B-HEXAHYDRO-1H-PYRIDO[2,1,-A]LSOQUINOLIN-2-YL 2-AMINO-3-METHYLBUTANOATE DI(4-METHYLBENZENESULFONATE)

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Patent in force

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07D 471/04 (2006.01)
European patent
(11) Number of the document 3394057
(13) Kind of document T
(96) European patent application number 16823529.9
Date of filing the European patent application 2016-12-22
(97) Date of publication of the European application 2018-10-31
(45) Date of publication and mention of the grant of the patent 2022-03-30
(46) Date of publication of the claims translation 2022-06-27
PCT application
(86) Number PCT/US2016/068277
Date 2016-12-22
PCT application publication
(87) Number WO 2017/112857
Date 2017-06-29
Priority applications
(30) Number Date Country code
201562387442 P 2015-12-23 US
Inventors
(72)
MCGEE, Kevin , US
LI, Bin-Feng , CN
Grantee
(73) NEUROCRINE BIOSCIENCES, INC. , 12780 El Camino Real, San Diego, CA 92130, US
Attorney or representative
(74) Jurga PETNIŪNAITĖ, AAA Law, A. Goštauto g. 40B, Verslo centras "Dvyniai", LT-03163 Vilnius, LT
Title
(54) Sintezės būdas, skirtas pagaminti (S)-(2R,3R,11bR)-3-izobutil-9,10-dimetoksi-2,3,4,6,7,11b-heksahidro-1H-pirido[2,1-a]izochinolin-2-ilo 2-amino-3-metilbutanoato di(4-metilbenzensulfonatą)
  SYNTHETIC METHOD FOR PREPARATION OF (S)-(2R,3R,11BR)-3-ISOBUTYL-9,10-DIMETHOXY-2,3,4,6,7,11B-HEXAHYDRO-1H-PYRIDO[2,1,-A]LSOQUINOLIN-2-YL 2-AMINO-3-METHYLBUTANOATE DI(4-METHYLBENZENESULFONATE)
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2026-12-22