Herbas VPB

Print
EN | LT
LT - (S)-N-(5-((R)-2-(2,5-difluorfenil)pirolidin-1-il)pirazolo[1,5-a]pirimidin-3-il)-3-hidroksipirolidin-1-karboksamido gavimas
EN - PREPARATION OF (S)-N-(5-((R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDIN-1-YL)PYRAZOLO[1,5-A]PYRIMIDIN-3-YL)-3-HYDROXYPYRROLIDINE-1-CARBOXAMIDE

Legal status

Patent in force

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07D 487/04 (2006.01)
A61K 31/5025 (2006.01)
A61P 35/00 (2006.01)
A61P 43/00 (2006.01)
European patent
(11) Number of the document 3458456
(13) Kind of document T
(96) European patent application number 17726442.1
Date of filing the European patent application 2017-05-18
(97) Date of publication of the European application 2019-03-27
(45) Date of publication and mention of the grant of the patent 2020-11-25
(46) Date of publication of the claims translation 2021-02-25
PCT application
(86) Number PCT/US2017/033257
Date 2017-05-18
PCT application publication
(87) Number WO 2017/201241
Date 2017-11-23
Priority applications
(30) Number Date Country code
201662338359 P 2016-05-18 US
Inventors
(72)
REYNOLDS, Mark, US
EARY, Charles Todd, US
SPENCER, Stacey, US
JUENGST, Derrick, US
HACHE, Bruno, US
JIANG, Yutong, US
HAAS, Julia, US
ANDREWS, Steven W., US
Grantee
(73) Array Biopharma Inc., 3200 Walnut Street, Boulder, CO 80301, US
Loxo Oncology, Inc., 281 Tresser Boulevard 9th Floor, Stamford, Connecticut 06901, US
Attorney or representative
(74) Reda ŽABOLIENĖ, METIDA, Verslo centras "VERTAS", Gynėjų g. 16, LT-01109 Vilnius, LT
Title
(54) (S)-N-(5-((R)-2-(2,5-difluorfenil)pirolidin-1-il)pirazolo[1,5-a]pirimidin-3-il)-3-hidroksipirolidin-1-karboksamido gavimas
  PREPARATION OF (S)-N-(5-((R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDIN-1-YL)PYRAZOLO[1,5-A]PYRIMIDIN-3-YL)-3-HYDROXYPYRROLIDINE-1-CARBOXAMIDE
Last renewal fee
Payment date Validity (years) Amount
2026-04-20 10 231.00 EUR
Next renewal fee
2027-05-18