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LT - 2,3-DISUBSTITUTED 1-ACYL-4-AMINO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE AS BROMODOMAIN INHIBITORS
EN - 2,3-DISUBSTITUTED 1-ACYL-4-AMINO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE AS BROMODOMAIN INHIBITORS

Legal status

Patent not validated

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07D 215/227 (2006.01)
C07D 401/12 (2013.01)
C07D 215/46 (2006.01)
C07D 413/04 (2013.01)
A61K 31/4375 (2013.01)
A61K 31/4706 (2006.01)
A61K 31/506 (2013.01)
C07D 401/04 (2006.01)
C07D 401/12 (2006.01)
A61K 31/496 (2013.01)
C07D 401/14 (2006.01)
C07D 215/46 (2013.01)
C07D 405/04 (2006.01)
A61K 31/5377 (2013.01)
C07D 405/14 (2006.01)
C07D 409/14 (2013.01)
C07D 409/14 (2006.01)
A61P 31/12 (2018.01)
C07D 413/04 (2006.01)
A61K 31/4706 (2013.01)
C07D 413/12 (2006.01)
C07D 215/227 (2013.01)
C07D 405/04 (2013.01)
C07D 413/14 (2006.01)
C07D 417/14 (2006.01)
C07D 471/08 (2013.01)
C07D 471/04 (2006.01)
A61K 31/4709 (2013.01)
C07D 487/08 (2006.01)
A61K 31/5386 (2013.01)
C07D 498/04 (2006.01)
A61K 31/497 (2013.01)
A61P 29/00 (2006.01)
C07D 417/12 (2013.01)
C07D 498/08 (2013.01)
European patent
(11) Number of the document 3511323
(13) Kind of document T
(96) European patent application number 18201850.7
Date of filing the European patent application 2014-03-12
(97) Date of publication of the European application 2019-07-17
(45) Date of publication and mention of the grant of the patent 2022-03-02
(46) Date of publication of the claims translation
Priority applications
(30) Number Date Country code
201361781583 P 2013-03-14 US
201361882798 P 2013-09-26 US
Inventors
(72)
AMANS, Dominique , GB
ATKINSON, Stephen John , GB
HARRISON, Lee Andrew , GB
HIRST, David Jonathan , GB
LAW, Robert Peter , GB
LINDON, Matthew , GB
PRESTON, Alexander , GB
SEAL, Jonathan Thomas , GB
WELLAWAY, Christopher Roland , GB
Grantee
(73) GlaxoSmithKline Intellectual Property (No.2) Limited , 980 Great West Road Brentford, Middlesex, TW8 9GS, GB
Title
(54) 2,3-DISUBSTITUTED 1-ACYL-4-AMINO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE AS BROMODOMAIN INHIBITORS
  2,3-DISUBSTITUTED 1-ACYL-4-AMINO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE AS BROMODOMAIN INHIBITORS