LT - N-{3-[3-ciklopropil-5-(2-fluor-4-jodfenilamino)-6,8-dimetil-2,4,7-triokso-3,4,6,7-tetrahidro- 2H-pirido[4,3-d]pirimidin-1-il]-fenil}-ciklopropankarboksamido dimetilsulfoksido solvatas kaip MEK1/2 inhibitorius
EN - N-{3-[3-CYCLOPROPYL-5-(2-FLUORO-4-IODOPHENYLAMINO)-6,8-DIMETHYL-2,4,7-TRIOXO-3,4,6,7-TETRAHYDRO-2H-PYRIDO[4,3-D]PYRIMIDIN-1-YL]-PHENYL}-CYCLOPROPANECARBOXAMIDE DIMETHYL SULPHOXIDE SOLVATE AS AN MEK1/2 INHIBITOR
Legal status
Patent lapsed (non-payment of fees)
Bibliographic data
Indications of the International Patent Classification (IPC)
| (51) |
INT.CL. |
C07D 471/04 |
(2006.01) |
|
|
A61P 35/00 |
(2006.01) |
|
|
A61K 31/519 |
(2006.01) |
European patent
| (11) |
Number of the document |
3524601 |
| (13) |
Kind of document |
T |
| (96) |
European patent application number |
16918763.0 |
|
Date of filing the European patent application |
2016-12-12 |
| (97) |
Date of publication of the European application |
2019-08-14 |
| (45) |
Date of publication and mention of the grant of the patent |
2021-10-13
|
| (46) |
Date of publication of the claims translation |
2021-12-27
|
PCT application
| (86) |
Number |
PCT/RU2016/000862 |
|
Date |
2016-12-12 |
PCT application publication
| (87) |
Number |
WO 2018/070900 |
|
Date |
2018-04-19 |
Priority applications
| (30) |
Number |
Date |
Country code |
|
2016139641 |
2016-10-10
|
RU |
Inventors
| (72) |
REPIK, Alexey Evgenievich , RU
IVACHTCHENKO, Alexandre Vasilievich , US
IGNATIEV, Vasily Gennadievich , RU
CHAFEEV, Mikhail Airatovich , RU
|
Grantee
| (73) |
R-Pharm Joint Stock Company (R-Pharm, JSC) ,
Berzarina str. 19 bld. 1, Moscow 123154,
RU
Repik, Alexey Evgenievich ,
54 Kotoroslnaya nab., Apt. 9, Yaroslavl, 150000,
RU
|
Attorney or representative
| (74) |
Ramunė GARŠVIENĖ,
Dūkštų g. 28-20, LT-07171 Vilnius,
LT
|
Title
| (54) |
N-{3-[3-ciklopropil-5-(2-fluor-4-jodfenilamino)-6,8-dimetil-2,4,7-triokso-3,4,6,7-tetrahidro- 2H-pirido[4,3-d]pirimidin-1-il]-fenil}-ciklopropankarboksamido dimetilsulfoksido solvatas kaip MEK1/2 inhibitorius |
| |
N-{3-[3-CYCLOPROPYL-5-(2-FLUORO-4-IODOPHENYLAMINO)-6,8-DIMETHYL-2,4,7-TRIOXO-3,4,6,7-TETRAHYDRO-2H-PYRIDO[4,3-D]PYRIMIDIN-1-YL]-PHENYL}-CYCLOPROPANECARBOXAMIDE DIMETHYL SULPHOXIDE SOLVATE AS AN MEK1/2 INHIBITOR |
Last renewal fee
|
Payment date |
Validity (years) |
Amount |
|
2021-12-01 |
6 |
139.00
EUR
|
Legal status
|
Patent lapsed (non-payment of fees)
|
|
|
Invalidation date |
2022-12-12 |
