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Legal status
Patent not validated
| (51) | INT.CL. | C07D 403/12 | (2006.01) |
| C07D 403/12 | (2013.01) | ||
| C07D 401/12 | (2006.01) | ||
| C07D 401/12 | (2013.01) | ||
| C07D 405/12 | (2006.01) | ||
| C07D 405/12 | (2013.01) | ||
| C07D 413/12 | (2006.01) | ||
| C07D 413/12 | (2013.01) | ||
| C07D 249/12 | (2006.01) | ||
| C07D 249/12 | (2013.01) | ||
| A61K 31/4196 | (2006.01) | ||
| A61P 29/00 | (2018.01) | ||
| A61P 35/02 | (2006.01) | ||
| A61P 35/00 | (2018.01) | ||
| A61P 35/02 | (2018.01) | ||
| A61P 43/00 | (2018.01) |
| (11) | Number of the document | 3532468 |
| (13) | Kind of document | T |
| (96) | European patent application number | 17788234.7 |
| Date of filing the European patent application | 2017-10-25 | |
| (97) | Date of publication of the European application | 2019-09-04 |
| (45) | Date of publication and mention of the grant of the patent | 2022-03-23 |
| (46) | Date of publication of the claims translation |
| (86) | Number | PCT/EP2017/077252 |
| Date | 2017-10-25 |
| (87) | Number | WO 2018/077923 |
| Date | 2018-05-03 |
| (30) | Number | Date | Country code |
| PCT/CN2016/103643 | 2016-10-27 | WO | |
| 201762569296 P | 2017-10-06 | US |
| (72) |
GRADL, Stefan, Nikolaus , DE
NGUYEN, Duy , DE
EIS, Knut , DE
GÜNTHER, Judith , DE
STELLFELD, Timo , DE
JANZER, Andreas , DE
CHRISTIAN, Sven , DE
MUELLER, Thomas , DE
EL SHEIKH, Sherif , DE
ZHOU, Han, Jie , US
ZHAO, Changjia , CN
SYKES, David Brian , US
FERRARA, Steven, James , US
LIU, Kery , CN
KRÖBER, Michael , DE
MERZ, Claudia , DE
NIEHUES, Michael , DE
SCHÄFER, Martina , DE
ZIMMERMANN, Katja , DE
NISING, Carl, Friedrich , DE
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| (73) |
Bayer Aktiengesellschaft ,
Kaiser-Wilhelm-Allee 1, 51373 Leverkusen,
DE
Bayer Pharma Aktiengesellschaft , Müllerstrasse 178, 13353 Berlin, DE The Broad Institute, Inc. , 415 Main Street, Cambridge, MA 02142, US President and Fellows of Harvard College , 17 Quincy Street, Cambridge, MA 02138, US The General Hospital Corporation , 55 Fruit Street, Boston, MA 02114, US |
| (54) | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH |
| 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH |