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Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C12N 15/113 (2010.01)
C12Y 304/21061 (2013.01)
A61K 31/712 (2006.01)
C12N 15/1137 (2013.01)
A61K 31/7125 (2006.01)
C12N2310/11 (2013.01)
A61P 3/06 (2006.01)
C12N2310/315 (2013.01)
C12N2310/3231 (2013.01)
C12N2310/3341 (2013.01)
C12N2310/341 (2013.01)
A61K 31/7125 (2013.01)
A61K 31/712 (2013.01)
A61P 3/06 (2018.01)
A61K 31/7115 (2013.01)
European patent
(11) Number of the document 3601569
(13) Kind of document T
(96) European patent application number 18772304.4
Date of filing the European patent application 2018-03-23
(97) Date of publication of the European application 2020-02-05
(45) Date of publication and mention of the grant of the patent 2023-09-27
(46) Date of publication of the claims translation
PCT application
(86) Number PCT/US2018/023936
Date 2018-03-23
PCT application publication
(87) Number WO 2018/175839
Date 2018-09-27
Priority applications
(30) Number Date Country code
201762476051 P 2017-03-24 US
Inventors
(72)
SWAYZE, Eric, E. , US
FREIER, Susan, M. , US
BUI, Huynh-Hoa , US
Grantee
(73) Ionis Pharmaceuticals, Inc. , 2855 Gazelle Court, Carlsbad, CA 92010, US
Title
(54) MODULATORS OF PCSK9 EXPRESSION
  MODULATORS OF PCSK9 EXPRESSION