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Legal status
Patent not validated
| (51) | INT.CL. | C07D 487/10 | (2006.01) |
| C07D 487/04 | (2013.01) | ||
| C07D 487/04 | (2006.01) | ||
| C07D 487/10 | (2013.01) | ||
| C07D 498/04 | (2006.01) | ||
| C07D 498/04 | (2013.01) | ||
| A61P 25/28 | (2006.01) | ||
| A61P 25/16 | (2018.01) | ||
| A61P 25/16 | (2006.01) | ||
| A61P 25/28 | (2018.01) | ||
| A61K 31/551 | (2006.01) |
| (11) | Number of the document | 3625234 |
| (13) | Kind of document | T |
| (96) | European patent application number | 18803112.4 |
| Date of filing the European patent application | 2018-05-17 | |
| (97) | Date of publication of the European application | 2020-03-25 |
| (45) | Date of publication and mention of the grant of the patent | 2023-09-20 |
| (46) | Date of publication of the claims translation |
| (86) | Number | PCT/US2018/033269 |
| Date | 2018-05-17 |
| (87) | Number | WO 2018/213634 |
| Date | 2018-11-22 |
| (30) | Number | Date | Country code |
| 201762507682 P | 2017-05-17 | US |
| (72) |
BONANOMI, Giorgio , US
ESTRADA, Anthony A. , US
FENG, Jianwen A. , US
FOX, Brian , US
FRANCINI, Cinzia Maria , US
HU, Cheng , US
LESLIE, Colin Philip , US
OSIPOV, Maksim , US
SUDHAKAR, Anantha , US
SWEENEY, Zachary K. , US
DE VICENTE FIDALGO, Javier , US
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| (73) |
Denali Therapeutics Inc. ,
161 Oyster Point Boulevard, South San Francisco, California 94080,
US
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| (54) | HEXAHYDROPYRAZOLO [1,2-A] DIAZEPINONES AND RELATED HETEROCYCLES AS INHIBITORS OF RIP-1 KINASE |
| HEXAHYDROPYRAZOLO [1,2-A] DIAZEPINONES AND RELATED HETEROCYCLES AS INHIBITORS OF RIP-1 KINASE |