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LT - 4-(4-(4-(((2-(2,6-dioksopiperidin-3-il)-1-oksoizoindolin-4-il)oksi) metil)benzil)piperazin-1-il)-3-fluorbenzonitrilas kaip antiproliferacinis junginys
EN - 4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-L-OXOISOINDOLIN-4-YL)OXY)METHYL)BENZYL)PIPERAZIN-L-YL)-3-FLUOROBENZONITRILE AS ANTIPROLIFERATIVE COMPOUND

Legal status

Patent in force

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. A61K 31/496 (2006.01)
C07D 401/04 (2006.01)
A61K 38/05 (2006.01)
A61K 31/573 (2006.01)
A61P 35/00 (2006.01)
A61K 45/06 (2006.01)
A61K 31/69 (2006.01)
European patent
(11) Number of the document 3651766
(13) Kind of document T
(96) European patent application number 18746444.1
Date of filing the European patent application 2018-07-09
(97) Date of publication of the European application 2020-05-20
(45) Date of publication and mention of the grant of the patent 2024-09-11
(46) Date of publication of the claims translation 2024-12-10
PCT application
(86) Number PCT/US2018/041230
Date 2018-07-09
PCT application publication
(87) Number WO 2019/014100
Date 2019-01-17
Priority applications
(30) Number Date Country code
201762530778 P 2017-07-10 US
201762593185 P 2017-11-30 US
201862675581 P 2018-05-23 US
Inventors
(72)
ALEXANDER, Matthew, D. , US
ARTMAN, Gerald, D., III , US
BRAY, Gordon, L. , US
CARMICHAEL, James , GB
CARRANCIO, Soraya , US
CATHERS, Brian E. , US
CORREA, Matthew, D. , US
HANSEN, Joshua , US
HAVENS, Courtney, G. , US
KERCHER, Timothy, S. , US
LOPEZ-GIRONA, Antonia , US
LU, Xiaoling , US
MAN, Hon-Wah , US
NAGY, Mark, A. , US
NARLA, Rama, K. , US
PICCOTTI, Joseph, R. , US
PIERCE, Daniel, W. , US
TAVARES-GRECO, Paula, A. , US
WHITEFIELD, Brandon, W. , US
WONG, Lilly, L. , US
ZOU, Nanfei , US
Grantee
(73) Celgene Corporation , Route 206 & Province Line Road, Princeton, NJ 08543, US
Attorney or representative
(74) Jurga PETNIŪNAITĖ, AAA Law, A. Goštauto g. 40B, Verslo centras "Dvyniai", LT-03163 Vilnius, LT
Title
(54) 4-(4-(4-(((2-(2,6-dioksopiperidin-3-il)-1-oksoizoindolin-4-il)oksi) metil)benzil)piperazin-1-il)-3-fluorbenzonitrilas kaip antiproliferacinis junginys
  4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-L-OXOISOINDOLIN-4-YL)OXY)METHYL)BENZYL)PIPERAZIN-L-YL)-3-FLUOROBENZONITRILE AS ANTIPROLIFERATIVE COMPOUND
Last renewal fee
Payment date Validity (years) Amount
2025-05-09 8 185.00 EUR
Next renewal fee
2026-07-09