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Legal status
Patent in force
| (51) | INT.CL. | C07D 513/22 | (2006.01) |
| C07D 515/22 | (2006.01) | ||
| A61P 11/00 | (2006.01) | ||
| A61K 31/437 | (2006.01) |
| (11) | Number of the document | 3752510 |
| (13) | Kind of document | T |
| (96) | European patent application number | 19707648.2 |
| Date of filing the European patent application | 2019-02-14 | |
| (97) | Date of publication of the European application | 2020-12-23 |
| (45) | Date of publication and mention of the grant of the patent | 2022-12-07 |
| (46) | Date of publication of the claims translation | 2023-04-11 |
| (86) | Number | PCT/US2019/018042 |
| Date | 2019-02-14 |
| (87) | Number | WO 2019/161078 |
| Date | 2019-08-22 |
| (30) | Number | Date | Country code |
| 201862631453 P | 2018-02-15 | US |
| (72) |
CLEMENS, Jeremy J. , US
ABELA, Alexander Russell , US
ANDERSON, Corey Don , US
BUSCH, Brett B. , US
CHEN, Weichao George , US
CLEVELAND, Thomas , US
COON, Timothy Richard , US
FRIEMAN, Bryan , US
GHIRMAI, Senait G. , US
GROOTENHUIS, Peter , US
GULEVICH, Anton V. , US
HADIDA RUAH, Sara Sabina , US
HSIA, Clara Kuang-Ju , US
KANG, Ping , US
KHATUYA, Haripada , US
MCCARTNEY, Jason , US
MILLER, Mark Thomas , US
PARASELLI, Prasuna , US
PIERRE, Fabrice , US
SWIFT, Sara E. , US
TERMIN, Andreas , US
UY, Johnny , US
VOGEL, Carl V. , US
ZHOU, Jinglan , US
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| (73) |
Vertex Pharmaceuticals Incorporated ,
50 Northern Avenue, Boston, MA 02210,
US
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| (74) |
Jurga PETNIŪNAITĖ,
AAA Law, A. Goštauto g. 40B, Verslo centras "Dvyniai", LT-03163 Vilnius,
LT
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| (54) | Makrocikliniai junginiai kaip cistinės fibrozės transmembraninio laidumo reguliatoriaus moduliatoriai, jų farmacinės kompozicijos, jų panaudojimas cistinės fibrozės gydymui ir jų gamybos būdas |
| MACROCYCLES AS MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS THEREOF, THEIR USE IN THE TREATMENT OF CYCSTIC FIBROSIS, AND PROCESS FOR MAKING THEM |
| Payment date | Validity (years) | Amount | |
| 2025-01-20 | 7 | 162.00 EUR |
| 2026-02-14 |