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LT - (S)-N-(5-((R)-2-(2,5-difluorfenil)pirolidin-1-il)pirazolo[1,5-a]pirimidin-3- il)-3-hidroksipirolidin-1-karboksamido gavimas
EN - PREPARATION OF (S)-N-(5-((R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDIN-1-YL)PYRAZOLO[1,5-A]PYRIMIDIN-3-YL)-3-HYDROXYPYRROLIDINE-1-CARBOXAMIDE

Legal status

Patent in force

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07D 487/04 (2006.01)
A61K 31/5025 (2006.01)
A61P 35/00 (2006.01)
A61P 43/00 (2006.01)
European patent
(11) Number of the document 3800189
(13) Kind of document T
(96) European patent application number 20208218.6
Date of filing the European patent application 2017-05-18
(97) Date of publication of the European application 2021-04-07
(45) Date of publication and mention of the grant of the patent 2023-06-28
(46) Date of publication of the claims translation 2023-10-10
Priority applications
(30) Number Date Country code
201662338359 P 2016-05-18 US
Inventors
(72)
REYNOLDS, Mark , US
EARY, Charles Todd , US
SPENCER, Stacey , US
JUENGST, Derrick , US
HACHE, Bruno , US
JIANG, Yutong , US
HAAS, Julia , US
ANDREWS, Steven W. , US
Grantee
(73) Loxo Oncology, Inc. , 281 Tresser Boulevard 9th Floor, Stamford, Connecticut 06901, US
Array Biopharma, Inc. , 3200 Walnut Street, Boulder, CO 80301, US
Attorney or representative
(74) Reda ŽABOLIENĖ, METIDA, Verslo centras "VERTAS", Gynėjų g. 16, LT-01109 Vilnius, LT
Title
(54) (S)-N-(5-((R)-2-(2,5-difluorfenil)pirolidin-1-il)pirazolo[1,5-a]pirimidin-3- il)-3-hidroksipirolidin-1-karboksamido gavimas
  PREPARATION OF (S)-N-(5-((R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDIN-1-YL)PYRAZOLO[1,5-A]PYRIMIDIN-3-YL)-3-HYDROXYPYRROLIDINE-1-CARBOXAMIDE
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2025-04-22 9 208.00 EUR
Next renewal fee
2026-05-18