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LT - THIOPHENOL-MALEIMIDE AND BROM-MALEIMIDE DERIVATIVES AS LINKER FOR ANTIBODY-DRUG CONJUGATES (ADC) FOR TREATING TUMORS
EN - THIOPHENOL-MALEIMIDE AND BROM-MALEIMIDE DERIVATIVES AS LINKER FOR ANTIBODY-DRUG CONJUGATES (ADC) FOR TREATING TUMORS

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Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07D 207/456 (2006.01)
A61P 35/00 (2018.01)
C07D 401/04 (2006.01)
C07K 16/32 (2013.01)
C07K 16/32 (2006.01)
C07K2317/92 (2013.01)
A61K 47/68 (2017.01)
C07D 207/456 (2013.01)
A61P 35/00 (2006.01)
C07D 401/04 (2013.01)
A61K 47/6889 (2017.08)
A61K 47/6849 (2017.08)
A61K 47/6851 (2017.08)
Y02P 20/55 (2015.11)
A61K 47/68031 (2023.08)
A61K 47/68033 (2023.08)
European patent
(11) Number of the document 3868409
(13) Kind of document T
(96) European patent application number 19900942.4
Date of filing the European patent application 2019-12-13
(97) Date of publication of the European application 2021-08-25
(45) Date of publication and mention of the grant of the patent 2024-07-17
(46) Date of publication of the claims translation
PCT application
(86) Number PCT/CN2019/124982
Date 2019-12-13
PCT application publication
(87) Number WO 2020/125546
Date 2020-06-25
Priority applications
(30) Number Date Country code
201811541356 2018-12-17 CN
Inventors
(72)
HUANG, Changjiang , CN
YE, Hui , CN
CHEN, Hu , CN
ZHAN, Xiuzhi , CN
SHEN, Nan , CN
LUO, Wenting , CN
HOU, Qiaohua , CN
FANG, Jianmin , CN
Grantee
(73) RemeGen Co., Ltd. , China (Shandong) Pilot Free Trade Zone Yantai District, Yantai Development Zone No.58 Beijing Middle Road, Shandong 264006, CN
Title
(54) THIOPHENOL-MALEIMIDE AND BROM-MALEIMIDE DERIVATIVES AS LINKER FOR ANTIBODY-DRUG CONJUGATES (ADC) FOR TREATING TUMORS
  THIOPHENOL-MALEIMIDE AND BROM-MALEIMIDE DERIVATIVES AS LINKER FOR ANTIBODY-DRUG CONJUGATES (ADC) FOR TREATING TUMORS