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LT - A MEK1 MUTATION CONFERRING RESISTANCE TO RAF AND MEK INHIBITORS
EN - A MEK1 MUTATION CONFERRING RESISTANCE TO RAF AND MEK INHIBITORS

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Patent not validated

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C12N 9/12 (2006.01)
C12N 9/1205 (2013.01)
A61P 35/00 (2006.01)
C12Q2600/106 (2013.01)
A61P 35/02 (2006.01)
C12Q2600/136 (2013.01)
A61P 35/04 (2006.01)
C12Q2600/156 (2013.01)
C12Q 1/6886 (2018.01)
C12Y 207/12002 (2013.01)
C12Q 1/6886 (2013.01)
A61P 35/00 (2018.01)
A61P 35/02 (2018.01)
A61P 35/04 (2018.01)
European patent
(11) Number of the document 3889254
(13) Kind of document T
(96) European patent application number 21158530.2
Date of filing the European patent application 2011-06-09
(97) Date of publication of the European application 2021-10-06
(45) Date of publication and mention of the grant of the patent 2024-08-14
(46) Date of publication of the claims translation
Priority applications
(30) Number Date Country code
35295910 P 2010-06-09 US
Inventors
(72)
GARRAWAY, Levi A , US
EMERY, Caroline , US
WAGLE, Nikhil , US
Grantee
(73) Dana-Farber Cancer Institute, Inc. , 450 Brookline Avenue, Boston, MA 02215, US
Title
(54) A MEK1 MUTATION CONFERRING RESISTANCE TO RAF AND MEK INHIBITORS
  A MEK1 MUTATION CONFERRING RESISTANCE TO RAF AND MEK INHIBITORS