LT - PROCESS FOR PREPARING AXITINIB, PROCESS FOR PURIFYING THE INTERMEDIATE 2-((3-IODO-1H-INDAZOL-6-YL)THIO)-N-METHYLBENZAMIDE, PROCESS FOR PURIFYING AXITINIB VIA THE AXITINIB HCL SALT, SOLID FORM OF THE AXITINIB HCL SALT
EN - PROCESS FOR PREPARING AXITINIB, PROCESS FOR PURIFYING THE INTERMEDIATE 2-((3-IODO-1H-INDAZOL-6-YL)THIO)-N-METHYLBENZAMIDE, PROCESS FOR PURIFYING AXITINIB VIA THE AXITINIB HCL SALT, SOLID FORM OF THE AXITINIB HCL SALT
Legal status
Patent not validated
Bibliographic data
Indications of the International Patent Classification (IPC)
| (51) |
INT.CL. |
C07D 401/06 |
(2006.01) |
|
|
C07D 401/06 |
(2013.01) |
|
|
C07D 231/56 |
(2006.01) |
|
|
A61P 35/00 |
(2018.01) |
|
|
A61K 31/4439 |
(2006.01) |
|
|
C07D 231/56 |
(2013.01) |
|
|
A61P 35/00 |
(2006.01) |
European patent
| (11) |
Number of the document |
3956321 |
| (13) |
Kind of document |
T |
| (96) |
European patent application number |
20717197.6 |
|
Date of filing the European patent application |
2020-04-09 |
| (97) |
Date of publication of the European application |
2022-02-23 |
| (45) |
Date of publication and mention of the grant of the patent |
2024-03-20
|
| (46) |
Date of publication of the claims translation |
|
PCT application
| (86) |
Number |
PCT/EP2020/060193 |
|
Date |
2020-04-09 |
PCT application publication
| (87) |
Number |
WO 2020/212253 |
|
Date |
2020-10-22 |
Priority applications
| (30) |
Number |
Date |
Country code |
|
19170258 |
2019-04-18
|
EP |
Inventors
| (72) |
CASTULIK, Jakub , CZ
SKOUMAL, Radomir , CZ
|
Grantee
| (73) |
Synthon B.V. ,
Microweg 22, 6545 CM Nijmegen,
NL
|
Title
| (54) |
PROCESS FOR PREPARING AXITINIB, PROCESS FOR PURIFYING THE INTERMEDIATE 2-((3-IODO-1H-INDAZOL-6-YL)THIO)-N-METHYLBENZAMIDE, PROCESS FOR PURIFYING AXITINIB VIA THE AXITINIB HCL SALT, SOLID FORM OF THE AXITINIB HCL SALT |
| |
PROCESS FOR PREPARING AXITINIB, PROCESS FOR PURIFYING THE INTERMEDIATE 2-((3-IODO-1H-INDAZOL-6-YL)THIO)-N-METHYLBENZAMIDE, PROCESS FOR PURIFYING AXITINIB VIA THE AXITINIB HCL SALT, SOLID FORM OF THE AXITINIB HCL SALT |
