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LT - Chinazolino junginys, skirtas G12D mutantinio KRAS baltymo degradacijai sukelti
EN - QUINAZOLINE COMPOUND FOR INDUCING DEGRADATION OF G12D MUTANT KRAS PROTEIN

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Patent in force

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07D 487/08 (2006.01)
A61K 31/517 (2006.01)
A61P 35/00 (2006.01)
European patent
(11) Number of the document 4293024
(13) Kind of document T
(96) European patent application number 22752854.4
Date of filing the European patent application 2022-02-14
(97) Date of publication of the European application 2023-12-20
(45) Date of publication and mention of the grant of the patent 2026-04-08
(46) Date of publication of the claims translation 2026-05-25
PCT application
(86) Number PCT/JP2022/005582
Date 2022-02-14
PCT application publication
(87) Number WO 2022/173032
Date 2022-08-18
Priority applications
(30) Number Date Country code
2021021656 2021-02-15 JP
Inventors
(72)
YOSHINARI, Tomohiro , JP
ISHIOKA, Hiroki , JP
KAWAMINAMI, Eiji , JP
WATANABE, Hideyuki , JP
KAWAGUCHI, Kenichi , JP
KURAMOTO, Kazuyuki , JP
IMAIZUMI, Tomoyoshi , JP
MORIKAWA, Takahiro , JP
HAMAGUCHI, Hisao , JP
IMADA, Sunao , JP
OKUMURA, Mitsuaki , JP
NAGASHIMA, Takeyuki , JP
INAMURA, Kohei , JP
Grantee
(73) Astellas Pharma Inc. , 5-1, Nihonbashi-Honcho 2-Chome, Chuo-ku Tokyo 103-8411, JP
Attorney or representative
(74) Reda ŽABOLIENĖ, METIDA, Verslo centras "VERTAS", Gynėjų g. 16, LT-01109 Vilnius, LT
Title
(54) Chinazolino junginys, skirtas G12D mutantinio KRAS baltymo degradacijai sukelti
  QUINAZOLINE COMPOUND FOR INDUCING DEGRADATION OF G12D MUTANT KRAS PROTEIN