Patent details

EN | LT

LT - PROCESS FOR THE MANUFACTURE OF THE CALCIUM SALT OF ROSUVASTATIN (E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[METHYL(METHYLSULFONYL)AMINO] PYRIMIDIN-5-YL](3R,5S)-3,5-DIHYDROXYHEPT-6-ENOIC ACID AND CRYSTALLINE INTERMEDIATES THEREOF

EN - PROCESS FOR THE MANUFACTURE OF THE CALCIUM SALT OF ROSUVASTATIN (E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[METHYL(METHYLSULFONYL)AMINO] PYRIMIDIN-5-YL](3R,5S)-3,5-DIHYDROXYHEPT-6-ENOIC ACID AND CRYSTALLINE INTERMEDIATES THEREOF

Legal status

Patent not validated

Bibliographic data

Indications of the International Patent Classification (IPC)
(51)	INT.CL.	C07D 405/06
		C07D 239/42

European patent
(11)	Number of the document	1682536
(13)	Kind of document	T
(96)	European patent application number	04768997.1
	Date of filing the European patent application	2004-10-22
(97)	Date of publication of the European application	2006-07-26
(45)	Date of publication and mention of the grant of the patent	2013-02-27
(46)	Date of publication of the claims translation

PCT application
(86)	Number	PCT/GB2004/004481
	Date	2004-10-22

PCT application publication
(87)	Number	WO 2005/042522
	Date	2005-05-12

Priority applications
(30)	Number	Date	Country code
	0324791	2003-10-24	GB

Inventors
(72)	OKADA, Tetsuo, Shionogi & Company Limited, JP HORBURY, John, AstraZeneca, GB LAFFAN, David Dermot Patrick, AstraZeneca, GB

Grantee
(73)	AstraZeneca UK Limited, 2 Kingdom Street, London W2 6BD, GB SHIONOGI & CO., LTD., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka 541-0045, JP

Title
(54)	PROCESS FOR THE MANUFACTURE OF THE CALCIUM SALT OF ROSUVASTATIN (E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[METHYL(METHYLSULFONYL)AMINO] PYRIMIDIN-5-YL](3R,5S)-3,5-DIHYDROXYHEPT-6-ENOIC ACID AND CRYSTALLINE INTERMEDIATES THEREOF
	PROCESS FOR THE MANUFACTURE OF THE CALCIUM SALT OF ROSUVASTATIN (E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[METHYL(METHYLSULFONYL)AMINO] PYRIMIDIN-5-YL](3R,5S)-3,5-DIHYDROXYHEPT-6-ENOIC ACID AND CRYSTALLINE INTERMEDIATES THEREOF