LT - Combination comprising the MEK inhibitor N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo- phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide and the Akt inhibitor N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]et
EN - Combination comprising the MEK inhibitor N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo- phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide and the Akt inhibitor N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]et
Teisinis statusas
Patentas neįsigaliojo (pagal EPK)
Bibliografiniai duomenys
Tarptautinės patentų klasifikacijos indeksai (TPK)
| (51) |
INT.CL. |
A01N 43/54 |
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A61K 31/415 |
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A61K 31/505 |
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Europos patentas
| (11) |
Patento numeris |
2480085 |
| (13) |
Dokumento rūšis |
T |
| (96) |
Europos patento paraiškos numeris |
10819438.2 |
|
Europos patento paraiškos padavimo data |
2010-09-23 |
| (97) |
Europos patento paraiškos paskelbimo data |
2012-08-01 |
| (45) |
Paskelbimo apie Europos patento išdavimą data |
2014-11-12
|
| (46) |
Apibrėžties vertimo paskelbimo data |
|
Tarptautinės paraiškos padavimo
| (86) |
Numeris |
PCT/US2010/049952 |
|
Data |
2010-09-23 |
Tarptautinės paraiškos paskelbimo
| (87) |
Numeris |
WO 2011/038085 |
|
Data |
2011-03-31 |
Prioriteto paraiškos
| (30) |
Numeris |
Data |
Šalis |
|
245027 P |
2009-09-23
|
US |
Išradėjai
| (72) |
DUMBLE, Melissa, US
GILMER, Tona, US
KUMAR, Rakesh, US
LEBOWITZ, Peter, F., US
MORRIS, Shannon, Renae, US
LAQUERRE, Sylvie, US
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Savininkas
| (73) |
GlaxoSmithKline LLC,
Corporation Service Company 2711 Centreville Road Suite 400, Wilmington, Delaware 19808,
US
|
Pavadinimas
| (54) |
Combination comprising the MEK inhibitor N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo- phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide and the Akt inhibitor N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]et |
| |
Combination comprising the MEK inhibitor N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo- phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide and the Akt inhibitor N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]et |
