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Legal status
Patent not validated
| (51) | INT.CL. | C07D 405/12 | |
| A61K 31/404 | |||
| A61P 11/00 |
| (11) | Number of the document | 2563778 |
| (13) | Kind of document | T |
| (96) | European patent application number | 11713134.2 |
| Date of filing the European patent application | 2011-03-25 | |
| (97) | Date of publication of the European application | 2013-03-06 |
| (45) | Date of publication and mention of the grant of the patent | 2016-08-24 |
| (46) | Date of publication of the claims translation |
| (86) | Number | PCT/US2011/030032 |
| Date | 2011-03-25 |
| (87) | Number | WO 2011/119984 |
| Date | 2011-09-29 |
| (30) | Number | Date | Country code |
| 321636 P | 2010-04-07 | US | |
| 321561 P | 2010-04-07 | US | |
| 319953 P | 2010-04-01 | US | |
| 317376 P | 2010-03-25 | US |
| (72) |
KESHAVARZ-SHOKRI, Ali, US
ZHANG, Beili, US
ALCACIO, Tim, Edward, US
LEE, Elaine, Chungmin, US
ZHANG, Yuegang, US
KRAWIEC, Mariusz, US
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| (73) |
Vertex Pharmaceuticals Incorporated,
50 Northern Avenue, Boston, MA 02210,
US
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| (54) | CRYSTALLINE FORM OF (R)-1(2,2 -DIFLUOROBENZO[D][1,3]DIOXOL-5YL)-N-(1-(2,3-DIHYDEROXYPROPYL)-6-FLUORO-2-(1-HYDROXY-2-METHYLPROPAN-2YL)-1H-INDOL-5YL)CYCLOPROPANECARBOXAMIDE |
| CRYSTALLINE FORM OF (R)-1(2,2 -DIFLUOROBENZO[D][1,3]DIOXOL-5YL)-N-(1-(2,3-DIHYDEROXYPROPYL)-6-FLUORO-2-(1-HYDROXY-2-METHYLPROPAN-2YL)-1H-INDOL-5YL)CYCLOPROPANECARBOXAMIDE |