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LT - Use of (S)-pyrrolidine-1,2-dicarboxylic acid 2-amide 1-({4-methyl-5-[2-(2,2,2-trifluoro-1,1-dimethyl-ethyl)- pyridin-4-yl]-thiazol-2-yl}-amide) in the treatment of EGFR dependent diseases or diseases that have acquired resistance to agents that target E
EN - Use of (S)-pyrrolidine-1,2-dicarboxylic acid 2-amide 1-({4-methyl-5-[2-(2,2,2-trifluoro-1,1-dimethyl-ethyl)- pyridin-4-yl]-thiazol-2-yl}-amide) in the treatment of EGFR dependent diseases or diseases that have acquired resistance to agents that target E

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Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. A61K 31/4439
A61K 31/517
A61K 39/395
A61K 45/06
A61P 35/00
C07K 16/32
A61K 39/00
European patent
(11) Number of the document 2637661
(13) Kind of document T
(96) European patent application number 11782111.6
Date of filing the European patent application 2011-11-07
(97) Date of publication of the European application 2013-09-18
(45) Date of publication and mention of the grant of the patent 2017-12-20
(46) Date of publication of the claims translation
PCT application
(86) Number PCT/EP2011/069522
Date 2011-11-07
PCT application publication
(87) Number WO 2012/062694
Date 2012-05-18
Priority applications
(30) Number Date Country code
411117 P 2010-11-08 US
Inventors
(72)
BRACHMANN, Saskia Maria, CH
FRITSCH, Christine, CH
MAIRA, Sauveur-Michel, CH
SCHNELL, Christian René, CH
GARCIA-ECHEVERRIA, Carlos, FR
Grantee
(73) Novartis AG, Lichtstrasse 35, 4056 Basel, CH
Title
(54) Use of (S)-pyrrolidine-1,2-dicarboxylic acid 2-amide 1-({4-methyl-5-[2-(2,2,2-trifluoro-1,1-dimethyl-ethyl)- pyridin-4-yl]-thiazol-2-yl}-amide) in the treatment of EGFR dependent diseases or diseases that have acquired resistance to agents that target E
  Use of (S)-pyrrolidine-1,2-dicarboxylic acid 2-amide 1-({4-methyl-5-[2-(2,2,2-trifluoro-1,1-dimethyl-ethyl)- pyridin-4-yl]-thiazol-2-yl}-amide) in the treatment of EGFR dependent diseases or diseases that have acquired resistance to agents that target E