LT - PHARMACEUTICALLY ACCEPTABLE SALT OF (E)-N-[4-[[3-CHLORO-4-(2-PYRIDYLMETHOXY)PHENYL]AMINO]-3-CYANO-7-ETHOXY-6-QUINOLYL]-3-[(2R)-1-METHYLPYRROLIDIN-2-YL]PROP-2-ENAMIDE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF
EN - PHARMACEUTICALLY ACCEPTABLE SALT OF (E)-N-[4-[[3-CHLORO-4-(2-PYRIDYLMETHOXY)PHENYL]AMINO]-3-CYANO-7-ETHOXY-6-QUINOLYL]-3-[(2R)-1-METHYLPYRROLIDIN-2-YL]PROP-2-ENAMIDE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF
Legal status
Patent not validated
Bibliographic data
Indications of the International Patent Classification (IPC)
(51) |
INT.CL. |
C07D 401/14 |
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A61K 31/4709 |
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A61P 35/00 |
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European patent
(11) |
Number of the document |
2684877 |
(13) |
Kind of document |
T |
(96) |
European patent application number |
12757831.8 |
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Date of filing the European patent application |
2012-02-10 |
(97) |
Date of publication of the European application |
2014-01-15 |
(45) |
Date of publication and mention of the grant of the patent |
2016-10-19
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(46) |
Date of publication of the claims translation |
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PCT application
(86) |
Number |
PCT/CN2012/071015 |
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Date |
2012-02-10 |
PCT application publication
(87) |
Number |
WO 2012/122865 |
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Date |
2012-09-20 |
Priority applications
(30) |
Number |
Date |
Country code |
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201110062359 |
2011-03-11
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CN |
Inventors
(72) |
LI, Xin, CN
WANG, Bin, CN
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Grantee
(73) |
Shanghai Hengrui Pharmaceutical Co. Ltd.,
279 Wenjing Road, Minhang District Shanghai 200245,
CN
Jiangsu Hengrui Medicine Co. Ltd.,
No. 7 Kunlunshan Road Economic and Technological Development Zone Lianyungang, Jiangsu 222047,
CN
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Title
(54) |
PHARMACEUTICALLY ACCEPTABLE SALT OF (E)-N-[4-[[3-CHLORO-4-(2-PYRIDYLMETHOXY)PHENYL]AMINO]-3-CYANO-7-ETHOXY-6-QUINOLYL]-3-[(2R)-1-METHYLPYRROLIDIN-2-YL]PROP-2-ENAMIDE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF |
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PHARMACEUTICALLY ACCEPTABLE SALT OF (E)-N-[4-[[3-CHLORO-4-(2-PYRIDYLMETHOXY)PHENYL]AMINO]-3-CYANO-7-ETHOXY-6-QUINOLYL]-3-[(2R)-1-METHYLPYRROLIDIN-2-YL]PROP-2-ENAMIDE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF |