Patent details

EN | LT

LT - PROCESS FOR THE PREPARATION OF (R)-3-(6-(4-METHYLPHENYL)-PYRIDIN-3-YLOXY)-1-AZA-BICYCLO[2.2.2]OCTANE BY REACTING 5-CHLORO-2-(4-METHYLPHENYL)PYRIDINE WITH (R)-3-HYDROXY-1-AZA-BICYCLO[2.2.2]OCTANE

EN - PROCESS FOR THE PREPARATION OF (R)-3-(6-(4-METHYLPHENYL)-PYRIDIN-3-YLOXY)-1-AZA-BICYCLO[2.2.2]OCTANE BY REACTING 5-CHLORO-2-(4-METHYLPHENYL)PYRIDINE WITH (R)-3-HYDROXY-1-AZA-BICYCLO[2.2.2]OCTANE

Legal status

Patent not validated

Bibliographic data

Indications of the International Patent Classification (IPC)
(51)	INT.CL.	C07D 453/02
		A61K 31/439
		A61P 25/16
		A61P 25/18
		A61P 25/22
		A61P 25/24
		A61P 25/28

European patent
(11)	Number of the document	3075732
(13)	Kind of document	T
(96)	European patent application number	16162555.3
	Date of filing the European patent application	2012-07-12
(97)	Date of publication of the European application	2016-10-05
(45)	Date of publication and mention of the grant of the patent	2018-09-12
(46)	Date of publication of the claims translation

Priority applications
(30)	Number	Date	Country code
	201161508147 P	2011-07-15	US

Inventors
(72)	MARTERER, Wolfgang, CH PRASHAD, Mahavir, US VILLHAUER, Edwin Bernard, US WAYKOLE, Liladhar Murlidhar, US VIVELO, James Anthony, US SUTTER, Bertrand, CH BIANCHI, Jean-Claude, CH WU, Raeann, US HAR, Denis, US KARPINSKI, Piotr H., US PIGNONE, Massimo, CH STINGELIN, Doris, CH BUERGER, Eckart, CH

Grantee
(73)	Novartis AG, Lichtstrasse 35, 4056 Basel, CH

Title
(54)	PROCESS FOR THE PREPARATION OF (R)-3-(6-(4-METHYLPHENYL)-PYRIDIN-3-YLOXY)-1-AZA-BICYCLO[2.2.2]OCTANE BY REACTING 5-CHLORO-2-(4-METHYLPHENYL)PYRIDINE WITH (R)-3-HYDROXY-1-AZA-BICYCLO[2.2.2]OCTANE
	PROCESS FOR THE PREPARATION OF (R)-3-(6-(4-METHYLPHENYL)-PYRIDIN-3-YLOXY)-1-AZA-BICYCLO[2.2.2]OCTANE BY REACTING 5-CHLORO-2-(4-METHYLPHENYL)PYRIDINE WITH (R)-3-HYDROXY-1-AZA-BICYCLO[2.2.2]OCTANE