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LT - MACROCYCLIC COMPOUNDS AS IRAK1/4 INHIBITORS AND USES THEREOF
EN - MACROCYCLIC COMPOUNDS AS IRAK1/4 INHIBITORS AND USES THEREOF

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Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07D 487/18 (2006.01)
A61P 35/00 (2006.01)
A61P 3/10 (2006.01)
A61P 17/06 (2006.01)
A61P 19/02 (2006.01)
A61P 19/06 (2006.01)
A61P 19/10 (2006.01)
A61P 25/16 (2006.01)
A61P 25/28 (2006.01)
A61K 31/415 (2006.01)
European patent
(11) Number of the document 3253764
(13) Kind of document T
(96) European patent application number 16706472.4
Date of filing the European patent application 2016-02-05
(97) Date of publication of the European application 2017-12-13
(45) Date of publication and mention of the grant of the patent 2021-06-09
(46) Date of publication of the claims translation
PCT application
(86) Number PCT/US2016/016709
Date 2016-02-05
PCT application publication
(87) Number WO 2016/127025
Date 2016-08-11
Priority applications
(30) Number Date Country code
201562112374 P 2015-02-05 US
Inventors
(72)
CHEN, Xiaoling , US
YU, Henry , US
LAN, Ruoxi , US
JORAND-LEBRUN, Catherine , US
JOHNSON, Theresa L. , US
GOUTOPOULOS, Andreas , US
Grantee
(73) Merck Patent GmbH , Frankfurter Strasse 250, 64293 Darmstadt, DE
Title
(54) MACROCYCLIC COMPOUNDS AS IRAK1/4 INHIBITORS AND USES THEREOF
  MACROCYCLIC COMPOUNDS AS IRAK1/4 INHIBITORS AND USES THEREOF