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Legal status
Patent not validated
| (51) | INT.CL. | C07D 487/18 | (2006.01) |
| A61P 35/00 | (2006.01) | ||
| A61P 3/10 | (2006.01) | ||
| A61P 17/06 | (2006.01) | ||
| A61P 19/02 | (2006.01) | ||
| A61P 19/06 | (2006.01) | ||
| A61P 19/10 | (2006.01) | ||
| A61P 25/16 | (2006.01) | ||
| A61P 25/28 | (2006.01) | ||
| A61K 31/415 | (2006.01) |
| (11) | Number of the document | 3253764 |
| (13) | Kind of document | T |
| (96) | European patent application number | 16706472.4 |
| Date of filing the European patent application | 2016-02-05 | |
| (97) | Date of publication of the European application | 2017-12-13 |
| (45) | Date of publication and mention of the grant of the patent | 2021-06-09 |
| (46) | Date of publication of the claims translation |
| (86) | Number | PCT/US2016/016709 |
| Date | 2016-02-05 |
| (87) | Number | WO 2016/127025 |
| Date | 2016-08-11 |
| (30) | Number | Date | Country code |
| 201562112374 P | 2015-02-05 | US |
| (72) |
CHEN, Xiaoling , US
YU, Henry , US
LAN, Ruoxi , US
JORAND-LEBRUN, Catherine , US
JOHNSON, Theresa L. , US
GOUTOPOULOS, Andreas , US
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| (73) |
Merck Patent GmbH ,
Frankfurter Strasse 250, 64293 Darmstadt,
DE
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| (54) | MACROCYCLIC COMPOUNDS AS IRAK1/4 INHIBITORS AND USES THEREOF |
| MACROCYCLIC COMPOUNDS AS IRAK1/4 INHIBITORS AND USES THEREOF |