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Legal status
Patent not validated
| (51) | INT.CL. | A61K 31/5365 | (2013.01) |
| C07D 207/456 | (2006.01) | ||
| C07D 403/14 | (2006.01) | ||
| A61K 47/68 | (2017.08) | ||
| C07D 401/14 | (2006.01) | ||
| A61P 35/00 | (2018.01) | ||
| C07D 491/18 | (2006.01) | ||
| C07D 207/456 | (2013.01) | ||
| C07D 519/00 | (2006.01) | ||
| C07D 401/14 | (2013.01) | ||
| C07K 5/027 | (2006.01) | ||
| C07D 403/14 | (2013.01) | ||
| C07K 7/02 | (2006.01) | ||
| C07D 491/18 | (2013.01) | ||
| A61K 47/68 | (2017.01) | ||
| C07D 519/00 | (2013.01) | ||
| C07K 7/02 | (2013.01) | ||
| A61K 31/5365 | (2006.01) | ||
| A61P 35/00 | (2006.01) |
| (11) | Number of the document | 3546448 |
| (13) | Kind of document | T |
| (96) | European patent application number | 17873634.4 |
| Date of filing the European patent application | 2017-11-24 | |
| (97) | Date of publication of the European application | 2019-10-02 |
| (45) | Date of publication and mention of the grant of the patent | 2022-04-06 |
| (46) | Date of publication of the claims translation |
| (86) | Number | PCT/CN2017/112958 |
| Date | 2017-11-24 |
| (87) | Number | WO 2018/095422 |
| Date | 2018-05-31 |
| (30) | Number | Date | Country code |
| 201611093699 | 2016-11-25 | CN | |
| 201711169847 | 2017-11-22 | CN |
| (72) |
SHEN, Jingkang , CN
MENG, Tao , CN
MA, Lanping , CN
WANG, Xin , CN
PENG, Hongli , CN
ZHANG, Yongliang , CN
YU, Ting , CN
CHEN, Lin , CN
DU, Zhiyan , CN
WANG, Ying , CN
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| (73) |
Mabwell (Shanghai) Bioscience Co., Ltd. ,
Building 3
No.576 Libing Road, Pudong New Area
Shanghai,
CN
Jiangsu Mabwell Health Pharmaceutical R&D Co., Ltd. , 3F, National New Drug Innovation Base 1 Avenue, China Medical City Taizhou Jiangsu, CN |
| (54) | DI-SUBSTITUTED MALEIC AMIDE LINKER FOR ANTIBODY-DRUG CONJUGATING AND PREPARATION METHOD AND USE THEREOF |
| DI-SUBSTITUTED MALEIC AMIDE LINKER FOR ANTIBODY-DRUG CONJUGATING AND PREPARATION METHOD AND USE THEREOF |