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LT - IMPROVED METHOD FOR THE MANUFACTURE OF 3-[(1S)-1-IMIDAZO[1,2-A]PYRIDIN-6-YLETHYL]-5-(1-METHYLPYRAZOL-4-YL)TRIAZOLO[4,5-B]PYRAZINE AND POLYMORPHIC FORMS THEREOF
EN - IMPROVED METHOD FOR THE MANUFACTURE OF 3-[(1S)-1-IMIDAZO[1,2-A]PYRIDIN-6-YLETHYL]-5-(1-METHYLPYRAZOL-4-YL)TRIAZOLO[4,5-B]PYRAZINE AND POLYMORPHIC FORMS THEREOF

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Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07D 471/04 (2006.01)
C07D 519/00 (2013.01)
C07D 519/00 (2006.01)
C07D 471/04 (2013.01)
European patent
(11) Number of the document 3849977
(13) Kind of document T
(96) European patent application number 19769738.6
Date of filing the European patent application 2019-09-10
(97) Date of publication of the European application 2021-07-21
(45) Date of publication and mention of the grant of the patent 2023-07-19
(46) Date of publication of the claims translation
PCT application
(86) Number PCT/EP2019/074083
Date 2019-09-10
PCT application publication
(87) Number WO 2020/053198
Date 2020-03-19
Priority applications
(30) Number Date Country code
PCT/CN2018/104941 2018-09-11 WO
Inventors
(72)
TURNER, Andrew, Roy , GB
TURNER, Andrew, Timothy , GB
HOWELL, Gareth, Paul , GB
GALL, Malcolm, Allan, Young , GB
MULHOLLAND, Keith, Raymond , GB
ADLINGTON, Neil, Keith , GB
TIAN, Zhenping , CN
LIU, Bo , CN
GONG, Qisun , CN
YU, Wei , CN
Grantee
(73) Astrazeneca AB , 151 85 Södertälje, SE
Hutchison Medipharma Limited , Building 4 720 Cai Lun Road Pilot Free Zone, Shanghai 201203, CN
Title
(54) IMPROVED METHOD FOR THE MANUFACTURE OF 3-[(1S)-1-IMIDAZO[1,2-A]PYRIDIN-6-YLETHYL]-5-(1-METHYLPYRAZOL-4-YL)TRIAZOLO[4,5-B]PYRAZINE AND POLYMORPHIC FORMS THEREOF
  IMPROVED METHOD FOR THE MANUFACTURE OF 3-[(1S)-1-IMIDAZO[1,2-A]PYRIDIN-6-YLETHYL]-5-(1-METHYLPYRAZOL-4-YL)TRIAZOLO[4,5-B]PYRAZINE AND POLYMORPHIC FORMS THEREOF