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Legal status
Patent not validated
| (51) | INT.CL. | C07D 213/61 | (2006.01) |
| C07D 471/18 | (2013.01) | ||
| C07D 401/04 | (2006.01) | ||
| C07D 213/61 | (2013.01) | ||
| C07D 471/18 | (2006.01) | ||
| C07D 401/04 | (2013.01) |
| (11) | Number of the document | 3953334 |
| (13) | Kind of document | T |
| (96) | European patent application number | 20721374.5 |
| Date of filing the European patent application | 2020-04-10 | |
| (97) | Date of publication of the European application | 2022-02-16 |
| (45) | Date of publication and mention of the grant of the patent | 2023-11-22 |
| (46) | Date of publication of the claims translation |
| (86) | Number | PCT/US2020/027655 |
| Date | 2020-04-10 |
| (87) | Number | WO 2020/210613 |
| Date | 2020-10-15 |
| (30) | Number | Date | Country code |
| 201962832614 P | 2019-04-11 | US |
| (72) |
CUNIERE, Nicolas , US
FAN, Yu , US
KOLOTUCHIN, Sergei , US
MUKHERJEE, Subha , US
SIMMONS, Eric M. , US
SINGH, Amarjit , US
WEI, Carolyn S. , US
XIAO, Yi , US
YUAN, Changxia , US
ZHENG, Bin , US
WAGSCHAL, Simon Albert , CH
BROGGINI, Diego Fernando Domenico , CH
CAO, Duy Chi Trung , CH
CHERNICHENKO, Kostiantyn , BE
LEMAIRE, Sébastien François Emmanuel , BE
BEN HAIM, Cyril , BE
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| (73) |
Bristol-Myers Squibb Company ,
Route 206 and Province Line Road, Princeton, NJ 08543,
US
Janssen Pharmaceutica NV , Turnhoutseweg 30, 2340 Beerse, BE |
| (54) | NOVEL SYNTHETIC OPTIONS TOWARDS THE MANUFACTURE OF (6R,10S)-10- {4-[5-CHLORO-2-(4-CHLORO-1H-1,2,3-TRIAZOL-1-YL)PHENYL]-6-OXO-1(6H)- PYRIMIDINYL}- 1-(DIFLUOROMETHYL)-6-METHYL-1,4,7,8,9,10-HEXAHYDRO-11,15 -(METHENO)PYRAZOLO [4,3-B] [1,7] DIAZACYCLOTETRADECIN-5(6H)-ONE |
| NOVEL SYNTHETIC OPTIONS TOWARDS THE MANUFACTURE OF (6R,10S)-10- {4-[5-CHLORO-2-(4-CHLORO-1H-1,2,3-TRIAZOL-1-YL)PHENYL]-6-OXO-1(6H)- PYRIMIDINYL}- 1-(DIFLUOROMETHYL)-6-METHYL-1,4,7,8,9,10-HEXAHYDRO-11,15 -(METHENO)PYRAZOLO [4,3-B] [1,7] DIAZACYCLOTETRADECIN-5(6H)-ONE |