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LT - Mažamolekuliniai KRAS G12C mutanto inhibitoriai
EN - SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT

Legal status

Patent in force

Bibliographic data
Indications of the International Patent Classification (IPC)
(51) INT.CL. C07D 471/04 (2006.01)
C07D 498/04 (2006.01)
A61K 31/522 (2006.01)
A61P 35/00 (2006.01)
European patent
(11) Number of the document 4051678
(13) Kind of document T
(96) European patent application number 20815976.4
Date of filing the European patent application 2020-10-27
(97) Date of publication of the European application 2022-09-07
(45) Date of publication and mention of the grant of the patent 2026-03-04
(46) Date of publication of the claims translation 2026-05-11
PCT application
(86) Number PCT/US2020/057496
Date 2020-10-27
PCT application publication
(87) Number WO 2021/086833
Date 2021-05-06
Priority applications
(30) Number Date Country code
201962926879 P 2019-10-28 US
202063030014 P 2020-05-26 US
Inventors
(72)
BHARATHAN, Indu , US
GATHIAKA, Symon , US
GRAHAM, Thomas, H. , US
HAN, Yongxin , US
HENDERSON, Timothy , US
HENNESSY, Elisabeth , US
MA, Xiaoshen , US
OTTE, Ryan , US
PALANI, Anandan , US
SLOMAN, David, L. , US
Grantee
(73) Merck Sharp & Dohme LLC , 126 East Lincoln Avenue P.O. Box 2000, Rahway, New Jersey 07065, US
Attorney or representative
(74) Reda ŽABOLIENĖ, METIDA, Verslo centras "VERTAS", Gynėjų g. 16, LT-01109 Vilnius, LT
Title
(54) Mažamolekuliniai KRAS G12C mutanto inhibitoriai
  SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT